| Type | Description |
|---|---|
| Definition | pancreas specific transcription factor, 1a |
| Date | Results | Publications |
|---|---|---|
| 2020-10-31 13:19:00 | Positive autofeedback regulation of Ptf1a transcription generates the levels of PTF1A required to generate itch circuit neurons. | 32241803 |
| 2020-02-15 10:04:00 | Study show that necrotizing enterocolitis in neonate mice is accompanied by elevation of IL-23 and IL-22 and decreased production of pancreatic enzymes. Mechanistically, IL-22 acts directly at the level of pancreatic acinar cells to decrease expression of the PTF1a. These results show that augmented production of IL-23 and IL-22 in early life has a negative impact on pancreatic enzyme secretion and food absorption. | 31586069 |
| 2019-12-14 11:25:00 | forebrain Ptf1a is one of the earliest regulators for sexual differentiation of the brain. | 29972793 |
| 2019-10-19 11:37:00 | The homozygous model helps clarify the role PTF1A has on the homeostasis and pathogenesis of exocrine pancreas in mice. | 30361559 |
| 2019-06-01 11:08:00 | PTF1a induced gene expression of digestive enzymes and acinar-specific transcription factors. | 29719936 |
| Type | IDs |
|---|---|
| Synonymous | PTF1-p48, PTF1p48, bHLHa29 |
| Gene |
UniProtKB-ID:
PTF1A_MOUSE,
A2ATA7_MOUSE
UniprotKB:
Q9QX98,
A2ATA7
UniParc:
UPI00000229C4
EMBL:
AK007922,
BC138507,
AB035675,
AF298116,
AJ252156,
AB035674,
BC132505
Ensembl:
ENSMUSG00000026735
KO:
mmu:19213
|
| Nucleutide sequences |
EMBL-CDS:
BAA88249.1,
CAB65273.1,
BAA88247.1,
BAE43208.1,
AAG31604.1,
AAI38508.1,
AAI32506.1
Ensembl_TRS:
ENSMUST00000028068
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000028068
RefSeq:
NP_061279.2
|
| Others |
UniRef100:
UniRef100_Q9QX98
UniRef90:
UniRef90_Q9QX98
UniRef50:
UniRef50_Q9QX98
UniGene:
Mm.69647
CCDS:
CCDS15715.1
|