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192117 Syngap1

192117

Syngap1

synaptic Ras GTPase activating protein 1

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition synaptic Ras GTPase activating protein 1

研究结论

Date Results Publications
2015-05-09 12:35:00 Phosphorylation of synaptic GTPase-activating protein (synGAP) by Ca2+/calmodulin-dependent protein kinase II (CaMKII) and cyclin-dependent kinase 5 (CDK5) alters the ratio of its GAP activity toward Ras and Rap GTPases. 25533468
2012-01-21 10:25:00 Here, we characterize the distribution of SynGAP at the postsynaptic density under basal and depolarizing conditions in rat hippocampal neuronal cultures. 21736925
2010-01-21 00:00:00 In the hippocampal CA1 region, perinatal hypoxia insults (P10) led to a reduction in SynGAP expression associated with impairment in long-term spatial learning and memory 15500970
2010-01-21 00:00:00 results show that phosphorylation of synGAP by Ca(2+)/calmodulin-dependent protein kinase II increases its Ras GTPase-activating activity by 70-95%; identifed four major sites of phosphorylation 14970204
2010-01-21 00:00:00 MUPP1-SynGAPalpha complex dissociation triggers a mechanism for AMPAR enhancement that is distinct from activity-induced long term potentiation 18417361

名称对应

Type IDs
Synonymous Syngap
Gene
UniProtKB-ID: F1LQW8_RAT
UniprotKB: F1LQW8
UniParc: UPI0001B3CB3F
EMBL: AC128962
Ensembl: ENSRNOG00000000483
Nucleutide sequences
Ensembl_TRS: ENSRNOT00000040859
Protein sequencees
Ensembl_PRO: ENSRNOP00000044041
RefSeq: NP_851606.3, NP_001106880.2
Others
UniRef100: UniRef100_F1LQW8
UniRef90: UniRef90_Q9QUH6
UniRef50: UniRef50_Q9QUH6
UniGene: Rn.9908

全选

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研究热度

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