例如:"NBL1", "4681", "drought"
收藏
19188 Psme2

19188

Psme2

proteasome (prosome, macropain) activator subunit 2 (PA28 beta)

protein-coding

Mus musculus

基因描述

Type Description
Definition proteasome (prosome, macropain) activator subunit 2 (PA28 beta)

研究结论

Date Results Publications
2019-08-24 11:29:00 Overexpression of PA28alpha and concomitant upregulation of PA28beta protein reduces depressive-like behavior and enhances learning and memory in female mice. The overexpression of PA28alpha does not increase PA28alphabeta-dependent proteasome activity but could still be linked to its protective functions upon oxidative stress and proteinopathy. 30400847
2018-03-24 11:52:00 Study clarifies the subunit composition and arrangement of PA28ab and provides key insights into the assembly of an asymmetric complex from two highly homologous subunits. Differential scanning fluorimetry experiments and activity assays classify PA28alpha4beta3 as most stable and most active, indicating that this assembly might represent the physiologically relevant species. 28867616
2017-09-09 11:49:00 Increased PA28B expression is associated with viral myocarditis. 28278207
2012-05-19 11:43:00 Nrf2-dependent induction of proteasome and Pa28alphabeta regulator are required for adaptation to oxidative stress. 22308036
2011-06-04 10:37:00 demonstrate that PA28 and the proteasome immunosubunits use fundamentally different mechanisms to enhance the supply of MHC class I-binding peptides 21360704

名称对应

Type IDs
Synonymous AA589371, AI788882, PA28b
Gene
UniProtKB-ID: PSME2_MOUSE, G3X9V0_MOUSE, Q5SVP3_MOUSE
UniprotKB: P97372, G3X9V0, Q5SVP3
UniParc: UPI0000473750, UPI00000041B6
EMBL: AC174678, BC057859, AF060195, BC005680, AK012344, AB007138, AK088654, AF115502, AB053120, U60329, D87910, AK143556
Ensembl: ENSMUSG00000079197, ENSMUSG00000078153, ENSMUSG00000116285
KO: mmu:621823, mmu:19188
Nucleutide sequences
EMBL-CDS: AAH57859.1, BAB28175.1, AAC83999.1, AAH05680.1, BAB47405.1, BAA28837.1, AAC53296.1, BAC40481.1, AAD38121.1, BAE25433.1, BAA22040.1
Ensembl_TRS: ENSMUST00000230082, ENSMUST00000104958, ENSMUST00000161807, ENSMUST00000229642, ENSMUST00000111378
Protein sequencees
Ensembl_PRO: ENSMUSP00000155248, ENSMUSP00000155390, ENSMUSP00000100564, ENSMUSP00000123798, ENSMUSP00000107009
RefSeq: NP_001025026.1, NP_035320.1
Others
UniRef100: UniRef100_G3X9V0, UniRef100_P97372
UniRef90: UniRef90_P97372
UniRef50: UniRef50_P97372
UniGene: Mm.371573
CCDS: CCDS49494.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员