Type | Description |
---|---|
Definition | presenilin 2 |
Date | Results | Publications |
---|---|---|
2021-01-09 13:26:00 | Loss of presenilin 2 age-dependently alters susceptibility to acute seizures and kindling acquisition. | 31862541 |
2019-04-27 10:56:00 | PS1- and PS2-dependent substrate processing in murine cells lacking presenilins (PSs) or stably re-expressing human PS1 or PS2 in an endogenous PS-null (PSdKO) background, were studied. | 28994238 |
2019-04-20 11:01:00 | Study uncovers a role of PS in presynaptic mechanisms, through APP cleavage and regulation of Syt7, that highlights aberrant synaptic vesicle processing as a possible new pathway in Alzheimer's disease. | 30429473 |
2019-02-09 12:32:00 | The altered expressions of hippocampal microRNAs were associated to the imbalance between neurotoxic and neuroprotective functions and seemed to affect neurodegeneration in PSEN1/PSEN2 double knockout mice more severely than in wild-type mice. | 28879407 |
2017-12-23 12:47:00 | These observations illustrate a novel PS2-dependent means of modulating LPS-mediated immune responses and identify a functional distinction between PS1 and PS2 in innate immunity. | 26081153 |
Type | IDs |
---|---|
Synonymous | ALG-3, Ad4h, Alg3, PS-2, PS2, Psnl2, STM2 |
Gene |
UniProtKB-ID:
PSN2_MOUSE,
Q3U4P5_MOUSE,
A0A0R4J1F2_MOUSE
UniprotKB:
Q61144,
Q3U4P5,
A0A0R4J1F2
UniParc:
UPI00001D4720,
UPI000016C802,
UPI00000211B1,
UPI00001D471F
EMBL:
U57325,
AF038935,
AC132436,
U49111,
BC010403,
AK014706,
AK148111,
U57324,
AK154119
Ensembl:
ENSMUSG00000010609
KO:
mmu:19165
|
Nucleutide sequences |
EMBL-CDS:
AAB92660.1,
BAB29514.1,
AAH10403.1,
AAC52935.1,
AAC53311.1,
AAC52937.1,
BAE28350.1,
BAE32386.1
Ensembl_TRS:
ENSMUST00000111108,
ENSMUST00000010753,
ENSMUST00000111105,
ENSMUST00000111106,
ENSMUST00000111104
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000106737,
ENSMUSP00000010753,
ENSMUSP00000106734,
ENSMUSP00000106735,
ENSMUSP00000106733
RefSeq:
NP_001122077.1,
XP_011237078.1,
NP_035313.2,
XP_006496775.1
|
Others |
UniRef100:
UniRef100_A0A0R4J1F2,
UniRef100_Q61144,
UniRef100_Q3U4P5
UniRef90:
UniRef90_Q61144,
UniRef90_H0UX54
UniRef50:
UniRef50_Q61144,
UniRef50_P49810-2
UniGene:
Mm.330850
CCDS:
CCDS15567.1
|
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Refseq |
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