| Type | Description |
|---|---|
| Definition | phosphodiesterase 9A |
| Date | Results | Publications |
|---|---|---|
| 2015-02-14 12:53:00 | It is a cGMP degrading phosphodiesterases, in which, cGMP is an important intracellular messenger for synaptic plasticity and memory function. | 24746365 |
| 2010-01-21 00:00:00 | We here present, for the first time, the expression of PDE9A, PDE10A, and PDE11A in the trigeminovascular system; localisation indicates that they may have a role in pain pathways | 19445908 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
PDE9A_RAT
UniprotKB:
Q8QZV1
UniParc:
UPI00000E8863
EMBL:
BC161837,
AF372654,
AY145898,
AABR06100134,
AABR06100133,
AABR06100135,
AABR06100132
Ensembl:
ENSRNOG00000001174
KO:
rno:191569
|
| Nucleutide sequences |
EMBL-CDS:
AAN64274.1,
AAL99404.1,
AAI61837.1
Ensembl_TRS:
ENSRNOT00000001559
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000001559
RefSeq:
XP_008771016.1,
NP_612552.1,
XP_008771017.1,
XP_008771015.1,
XP_017457026.1
|
| Others |
UniRef100:
UniRef100_Q8QZV1
UniRef90:
UniRef90_O70628
UniRef50:
UniRef50_O76083-11
UniGene:
Rn.20981
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 26871637 |
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. Cell Xinping Yang , Jasmin Coulombe-Huntington , Shuli Kang , Gloria M Sheynkman , Tong Hao , Aaron Richardson , Song Sun , Fan Yang , Yun A Shen , Ryan R Murray , Kerstin Spirohn , Bridget E Begg , Miquel Duran-Frigola , Andrew MacWilliams , Samuel J Pevzner , Quan Zhong , Shelly A Trigg , Stanley Tam , Lila Ghamsari , Nidhi Sahni , Song Yi , Maria D Rodriguez , Dawit Balcha , Guihong Tan , Michael Costanzo , Brenda Andrews , Charles Boone , Xianghong J Zhou , Kourosh Salehi-Ashtiani , Benoit Charloteaux , Alyce A Chen , Michael A Calderwood , Patrick Aloy , Frederick P Roth , David E Hill , Lilia M Iakoucheva , Yu Xia , Marc Vidal |
2016-02-11 |
USH1C,
PQBP1,
OPTN,
RBM5,
CDK5,
CDK7,
RABEPK,
SRRM1,
NOD1,
CD2BP2,
RBM14,
HAX1,
SLC30A9,
STK25,
SEMA4F,
SLC19A2,
CETP,
SRSF10,
SEPT9,
ALDH1L1,
RCC1,
LDB3,
AKAP10,
SEC63,
PHF21B,
HELQ,
CKB,
ERCC8,
CLCN2,
ZFYVE27,
CLPTM1,
TTC8,
C15orf40,
COL1A2,
BBS5,
ACMSD,
DNAJC19,
CPA2,
C7orf34,
CRH,
CRK,
RDH12,
MIPOL1,
ZNF688,
SLC25A10,
NKX2-5,
CTNS,
CTSD,
UPP2,
CYBB,
CYP11A1,
TSTD2,
DAO,
REM2,
DYX1C1,
DCN,
DDC,
GLIS3,
DGUOK,
DHCR7,
DMD,
E2F6,
TYMP,
EGR2,
FLCN,
EPHX1,
EYA4,
ETFA,
ETV6,
FANCC,
FANCG,
EFEMP1,
MICU2,
ZUFSP,
FCGR3A,
ABCB7,
FGA,
FGFR1,
FH,
DOLK,
KIAA0907,
ARHGEF15,
SETX,
ARHGAP26,
SPG20,
FMO3,
ETHE1,
SLC39A14,
CDK20,
SMUG1,
FXN,
FTSJ1,
MCM9,
GABRA2,
GAD1,
SUMF2,
GALT,
UNC50,
FBXO8
|
| 25799991 |
Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease. Nature Dong I Lee , Guangshuo Zhu , Takashi Sasaki , Gun-Sik Cho , Nazha Hamdani , Ronald Holewinski , Su-Hyun Jo , Thomas Danner , Manling Zhang , Peter P Rainer , Djahida Bedja , Jonathan A Kirk , Mark J Ranek , Wolfgang R Dostmann , Chulan Kwon , Kenneth B Margulies , Jennifer E Van Eyk , Walter J Paulus , Eiki Takimoto , David A Kass |
2015-03-26 |
Pde9a,
PDE9A
|
| 24746365 |
PDE9A inhibition rescues amyloid beta-induced deficits in synaptic plasticity and cognition. Neurobiol. Aging Katja S Kroker , Chantal Mathis , Anelise Marti , Jean-Christophe Cassel , Holger Rosenbrock , Cornelia Dorner-Ciossek |
2014-09-01 |
Pde9a,
Anks1b
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 19445908 |
PDE9A, PDE10A, and PDE11A expression in rat trigeminovascular pain signalling system. Brain Res. Lars S Kruse , Morten Møller , Maiken Tibaek , Steen Gammeltoft , Jes Olesen , Christina Kruuse |
2009-07-24 |
Pde11a,
Pde9a,
Pde10a
|
| 16780588 |
BMC Genomics Yu-Hui Hu , Hans-Jörg Warnatz , Dominique Vanhecke , Florian Wagner , Andrea Fiebitz , Sabine Thamm , Pascal Kahlem , Hans Lehrach , Marie-Laure Yaspo , Michal Janitz |
2006-01-01 |
DSCR3,
B3GALT5,
CCT8,
WDR4,
HSF2BP,
CXADR,
ETS2,
RRP1B,
CLDN14,
C2CD2,
CLDN17,
DNMT3L,
HLCS,
HMGN1,
KRTAP6-1,
IFNGR2,
KCNA5,
KCNE1,
KCNJ6,
MX1,
MEMO1,
PCP4,
PDE9A,
PFKL,
PKNOX1,
UBASH3A,
BRWD1,
PCBP3,
LRRC3DN,
PPIA,
C21orf59,
AGPAT3,
MAP3K7CL,
BACH1,
SH3BGR,
TMPRSS3,
UBE2G2,
TMEM50B,
RUNX1-IT1,
CHAF1B,
LINC01547,
PDXK,
RRP1,
CBS,
MCM3AP,
RSPH1,
CLDN8,
PAXBP1,
ABCG1,
CRYZL1,
KCNE2
|
| 12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
| 9624145 |
Identification and characterization of a novel family of cyclic nucleotide phosphodiesterases. J Biol Chem S H Soderling , S J Bayuga , J A Beavo |
1998-06-19 | - |
| 9624146 |
Isolation and characterization of PDE9A, a novel human cGMP-specific phosphodiesterase. J Biol Chem D A Fisher , J F Smith , J S Pillar , S H St Denis , J B Cheng |
1998-06-19 | - |
| 14501210 |
Cloning and localization of the cGMP-specific phosphodiesterase type 9 in the rat brain. J. Neurocytol. W C G van Staveren , J Glick , M Markerink-van Ittersum , M Shimizu , J A Beavo , H W M Steinbusch , J de Vente |
1700-01-01 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
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|---|---|---|
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