| Type | Description |
|---|---|
| Definition | kallikrein related-peptidase 6 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:52:00 | KLK6 expression in skin induces PAR1-mediated psoriasiform dermatitis and inflammatory joint disease. | 32155135 |
| 2020-04-04 10:43:00 | Elimination of Klk6 in Spink5 KO mice (model for Netherton syndrome (NS) remarkably suppresses the expression of Tslp, a major itching-inducing factor and driver of allergic reactions during differentiation of epidermal keratinocytes. Study demonstrated for the first time that KLK6 is implicated in skin inflammation and may represent a novel druggable target for NS and other inflammatory conditions e.g. atopic dermatitis. | 31255470 |
| 2019-05-18 10:15:00 | The data are exciting because they demonstrate that Klk6 can influence astrocyte plasticity through receptor-dependent mechanisms. | 29604205 |
| 2018-10-06 10:12:00 | expression strongly induced in psoriasiform epidermis; crucial for development of imiquimod-induced psoriasiform dermatitis | 27621228 |
| 2018-07-21 12:08:00 | Kallikrein 6 secreted by oligodendrocytes plays a critical role in the pathogenesis of experimental autoimmune encephalomyelitis. | 29086442 |
| Type | IDs |
|---|---|
| Synonymous | AI849898, BSP, Bssp, Klk29, MSP, Prss18, Prss9, neurosin |
| Gene |
UniProtKB-ID:
Q91Y82_MOUSE
UniprotKB:
Q91Y82
UniParc:
UPI0000029600
EMBL:
AB008928,
AC134858,
AK138218,
BC031119
Ensembl:
ENSMUSG00000050063
KO:
mmu:19144
|
| Nucleutide sequences |
EMBL-CDS:
AAH31119.1,
BAE23586.1,
BAB55605.1
Ensembl_TRS:
ENSMUST00000107968,
ENSMUST00000107967,
ENSMUST00000107966
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000103602,
ENSMUSP00000103600,
ENSMUSP00000103601
RefSeq:
XP_030098097.1,
NP_035307.2,
NP_001158169.1,
NP_001158170.1,
NP_001158168.1
|
| Others |
UniRef100:
UniRef100_A0A1R3UGK6
UniRef90:
UniRef90_A0A0B6VLS7
UniRef50:
UniRef50_I3M8B4
UniGene:
Mm.3944
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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