| Type | Description |
|---|---|
| Definition | suppression of tumorigenicity 14 (colon carcinoma) |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:18:00 | Proteolytic cleavage of Podocin by Matriptase exacerbates podocyte injury. | 32907879 |
| 2020-07-11 10:20:00 | matriptase is a causative agent in the development of congenital tufting enteropathy (CTE) and may provide a new target for the treatment of CTE in individuals carrying SPINT2 mutation | 31628112 |
| 2019-06-29 12:57:00 | The catalytic, stem, and transmembrane portions of matriptase-2 are required for suppressing the expression of the iron-regulatory hormone hepcidin. | 30559294 |
| 2017-09-09 12:11:00 | These results identify EpCAM as a substrate of matriptase and link HAI-2, matriptase, EpCAM, and claudin-7 in a functionally important pathway that causes disease when it is dysregulated. | 28094766 |
| 2016-04-09 10:41:00 | The proliferation impairment in matriptase-deficient breast cancer cells is caused by their inability to initiate activation of the c-Met signalling pathway in response to fibroblast-secreted pro-HGF. | 25873032 |
| Type | IDs |
|---|---|
| Synonymous | Epithin, MT-SP1, Prss14, Tmprss14, mCAP3, matriptase |
| Gene |
UniProtKB-ID:
ST14_MOUSE,
Q543E3_MOUSE
UniprotKB:
P56677,
Q543E3
UniParc:
UPI00000040CC
EMBL:
AF042822,
AK166745,
AK052738,
BC005496
Ensembl:
ENSMUSG00000031995
KO:
mmu:19143
|
| Nucleutide sequences |
EMBL-CDS:
AAH05496.1,
AAD02230.3,
BAC35125.1,
BAE38987.1
Ensembl_TRS:
ENSMUST00000034478
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000034478
RefSeq:
XP_006510161.1,
NP_035306.2,
XP_036010597.1,
XP_006510162.1
|
| Others |
UniRef100:
UniRef100_P56677
UniRef90:
UniRef90_P56677
UniRef50:
UniRef50_P56677
UniGene:
Mm.243926
CCDS:
CCDS22948.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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