| Type | Description |
|---|---|
| Definition | protease, serine 12 neurotrypsin (motopsin) |
| Date | Results | Publications |
|---|---|---|
| 2020-04-11 10:05:00 | This study determined the crystal structure of the third scavenger receptor cysteine-rich (SRCR) domain of murine neurotrypsin, immediately preceding the C-terminal serine-protease (SP) domain and performed a comparative structural analysis using homologous SRCR structures. | 30748049 |
| 2014-02-15 11:58:00 | This study identifies Tequila and neurotrypsin as new genes repressed by presenilins and reveals a novel mechanism used by presenilins to modulate CREB signaling based on controlling CREB recruitment. | 24145027 |
| 2013-10-26 12:38:00 | co-expression of sez-6 with motopsin restored the effect of motopsin at the basal level, while sez-6 expression alone showed no effects on cell morphology. Our results suggest that the interaction of motopsin and sez-6 modulates neuronal cell morphology | 23770366 |
| 2010-04-12 11:38:00 | Our results indicate that an extracellular protease, motopsin, preferentially affects social behaviors, and modulates the functions of hippocampal neurons. | 20092579 |
| 2010-01-21 00:00:00 | Detailed analyses indicated that presynaptic action potential firing is necessary for the release of neurotrypsin, whereas postsynaptic NMDA receptor activation is necessary for the neurotrypsin-dependent cleavage of agrin. | 19303856 |
| Type | IDs |
|---|---|
| Synonymous | Bssp-3, motopsin |
| Gene |
UniProtKB-ID:
NETR_MOUSE
UniprotKB:
O08762
UniParc:
UPI0000001A87
EMBL:
BC031429,
Y13192,
D89871
Ensembl:
ENSMUSG00000027978
KO:
mmu:19142
|
| Nucleutide sequences |
EMBL-CDS:
BAA23986.1,
CAA73646.1,
AAH31429.1
Ensembl_TRS:
ENSMUST00000029603
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000029603
RefSeq:
NP_032965.1
|
| Others |
UniRef100:
UniRef100_O08762
UniRef90:
UniRef90_O08762
UniRef50:
UniRef50_O08762
UniGene:
Mm.9431
CCDS:
CCDS17817.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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