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191275 kri-1

191275

kri-1

human KRIT 1 (Krev interaction trapped/cerebral cavernous malformation 1) homolog

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition human KRIT 1 (Krev interaction trapped/cerebral cavernous malformation 1) homolog

研究结论

Date Results Publications
2019-05-25 11:36:00 Study define the apoptotic pathway downstream of KRI-1 by conducting a forward genetic mutagenesis screen to restore ionizing radiation-induced apoptosis in kri-1 mutant worms. Proteomic analysis of KRI-1 binding partners identifies the previously uncharacterized protein K07A9.3, which is the ortholog of human CCM2 and a regulator of the ERK-5 pathway. 30996251
2010-06-14 11:43:00 Kri-1 is required to activate DNA damage-dependent cell death of germ cells independently of cep-1/p53. 20137949
2010-01-21 00:00:00 Data show that the reproductive system communicates with the intestine through lipophilic-hormone signaling and that a gene called kri-1 is likely to act in the intestine to promote DAF-16 nuclear localization in response to this signal. 16530050

名称对应

Type IDs
Gene
UniProtKB-ID: G5EDH0_CAEEL, G5EF18_CAEEL
UniprotKB: G5EDH0, G5EF18
UniParc: UPI00004C3C6E, UPI00004C3C6F
EMBL: BX284601, DQ372920
EnsemblGenome: WBGene00013955
KO: cel:CELE_ZK265.1
Nucleutide sequences
EMBL-CDS: CAB03514.2, ABD16184.1, CAI46592.1
Gene_ORFName: ZK265.1, CELE_ZK265.1, ZK265.1, CELE_ZK265.1
Protein sequencees
RefSeq: NP_001021863.1, NP_001021864.1
Others
UniRef100: UniRef100_G5EDH0, UniRef100_G5EF18
UniRef90: UniRef90_G5EDH0
UniRef50: UniRef50_G5EDH0
UniGene: Cel.25055

全选

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研究热度

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