| Type | Description |
|---|---|
| Definition | protein C |
| Date | Results | Publications |
|---|---|---|
| 2020-07-11 10:41:00 | APC inhibits LPS-mediated cytoplasmic translocation and secretion of HMGB1 in endothelial cells by epigenetic mechanisms | 30865333 |
| 2019-10-26 12:39:00 | there is a predilection of low protein C-induced spontaneous atherothrombosis in Apoe(-/-) mice for the right coronary sinus. | 30305662 |
| 2019-03-23 12:01:00 | These results support the concept that APC-induced, PAR1-dependent biased signaling following R46 cleavage is central to the in vivo benefits of APC. | 29343482 |
| 2017-12-09 14:04:00 | Data show that activated protein C signals via protease activated receptors PAR2/PAR3 to expand Treg cells, mitigating the disease in mice. | 28827518 |
| 2017-09-30 10:35:00 | insulin and aPC converge on a common spliced-X-box binding protein-1 (sXBP1) signaling pathway to maintain endoplasmic reticulum (ER) homeostasis. | 28687614 |
| Type | IDs |
|---|---|
| Synonymous | PC |
| Gene |
UniProtKB-ID:
PROC_MOUSE
UniprotKB:
P33587
UniParc:
UPI00000E6FA7
EMBL:
BC013896,
D10445,
D43755,
AF034569,
AF318182
Ensembl:
ENSMUSG00000024386
KO:
mmu:19123
|
| Nucleutide sequences |
EMBL-CDS:
AAH13896.1,
AAK07918.1,
BAA07812.1,
AAC33795.1,
BAA01235.1
Ensembl_TRS:
ENSMUST00000234651,
ENSMUST00000171765
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000157269,
ENSMUSP00000132226
RefSeq:
NP_001036233.2,
XP_006525785.1,
NP_001036232.1,
XP_030106222.1,
NP_032960.3,
XP_011245159.1,
XP_006525784.1,
NP_001300867.1
|
| Others |
UniRef100:
UniRef100_P33587
UniRef90:
UniRef90_P33587
UniRef50:
UniRef50_P33587
UniGene:
Mm.2786,
Mm.489734
CCDS:
CCDS29116.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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