| Type | Description |
|---|---|
| Definition | protein kinase, cAMP dependent regulatory, type I, alpha |
| Date | Results | Publications |
|---|---|---|
| 2020-08-22 15:27:00 | Identification of circular RNA-associated competing endogenous RNA network in the development of cleft palate. | 31074068 |
| 2019-11-02 12:02:00 | Study evaluated the role of signaling alterations in adrenal homeostasis and differentiation by generating mice with targeted Prkar1a genetic ablation specifically in adrenal cortex and proposed that cortex remodeling not only influences the establishment of adrenarche, but also is part of sexually dimorphic mechanisms that could help to explain the overrepresentation of adrenocortical diseases in women. | 29367455 |
| 2019-02-09 11:27:00 | Mice with a genetic background of Tpo-Cre;Prkar1a(flox/flox);Epac1(-/-) are aggressive, and both the thyroid-specific knockout of Prkar1a and global knockout of Epac1 likely contribute to this aggressive behavior. This study supports the hypothesis that altered thyroid signaling and aggressive behavior are linked. | 29289659 |
| 2018-02-17 11:28:00 | This mouse knockout model supports the role of prkar1a as a tumor suppressor gene in the pancreas and points to the pathway as a possible therapeutic target for these lesions. | 27803029 |
| 2018-01-13 10:15:00 | This model, the first describing the germline expression of a PRKAR1A mutation causing dominant repression of cAMP-dependent reproduced the main features of acrodysostosis 1 in humans. | 27589370 |
| Type | IDs |
|---|---|
| Synonymous | 1300018C22Rik, RIalpha, Tse-1, Tse1 |
| Gene |
UniProtKB-ID:
KAP0_MOUSE,
Q3TYK4_MOUSE
UniprotKB:
Q9DBC7,
Q3TYK4
UniParc:
UPI00005AD1FA,
UPI0000021990
EMBL:
AK005039,
AK051068,
AK027916,
AK147188,
BC005697,
AK145797,
AK151124,
AK145860,
AJ278427,
AJ278429,
AK158562,
AK153227,
BC003461,
AK150427
Ensembl:
ENSMUSG00000020612
KO:
mmu:19084
|
| Nucleutide sequences |
EMBL-CDS:
BAE26655.1,
AAH05697.1,
CAB94778.1,
BAE29550.1,
BAC25664.1,
BAE30132.1,
BAE27748.1,
AAH03461.1,
CAB94718.1,
BAE31820.1,
BAE26704.1,
BAB23766.1,
BAC34516.1,
BAE34559.1
Ensembl_TRS:
ENSMUST00000049527,
ENSMUST00000106677
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000056500,
ENSMUSP00000102288
RefSeq:
NP_001360841.1,
NP_001300902.1,
NP_001300904.1,
NP_001300905.1,
NP_001360842.1,
NP_068680.1,
NP_001349606.1,
XP_036012323.1,
NP_001300903.1
|
| Others |
UniRef100:
UniRef100_Q9DBC7
UniRef90:
UniRef90_Q9DBC7
UniRef50:
UniRef50_P31321
UniGene:
Mm.30039
CCDS:
CCDS25583.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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