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19065 Npy4r

19065

Npy4r

neuropeptide Y receptor Y4

protein-coding

Mus musculus

基因描述

Type Description
Definition neuropeptide Y receptor Y4

研究结论

Date Results Publications
2016-09-24 11:34:00 Genetic deletion of the Y4 receptor impaired fear extinction, an effect that was rescued by short-term fasting 26062787
2015-03-21 10:35:00 These data demonstrate glucose-regulated secretion of PP and its effects on glucagon release through PPYR1 receptors expressed by alpha-cells. 25445712
2011-04-23 10:20:00 Data describe the complex interaction between Y2/Y4 receptors in control of bone mass, and suggest that the reduction in cortical bone observed in the absence of leptin is due to the anti-osteogenic effect of elevated hypothalamic NPY levels. 20635164
2011-03-05 10:45:00 Data from studies in knockout mice suggest that signaling through Y4 receptor prevents development of short-/long-term anxiety-/depression-like behaviour caused by acute immune challenge. Study includes comparison with Y2 receptor knockout mice. 19939871
2011-01-15 10:32:00 Taken together, this work demonstrates the critical roles of Y2 and Y4 receptors in the regulation of body composition and energy metabolism, highlighting dual antagonism of Y2 and Y4 receptors as a potentially effective anti-obesity treatment. 20881101

名称对应

Type IDs
Synonymous NYYR-D, Ppyr1, Y4
Gene
UniProtKB-ID: NPY4R_MOUSE
UniprotKB: Q61041
UniParc: UPI0000021D7D
EMBL: AK144461, BC132395, U40189, BC145981
Ensembl: ENSMUSG00000048337
KO: mmu:19065
Nucleutide sequences
EMBL-CDS: BAE25901.1, AAI45982.1, AAC52442.1, AAI32396.1
Ensembl_TRS: ENSMUST00000052164
Protein sequencees
Ensembl_PRO: ENSMUSP00000056576
RefSeq: NP_032945.3
Others
UniRef100: UniRef100_Q61041
UniRef90: UniRef90_Q63447
UniRef50: UniRef50_Q63447
UniGene: Mm.57059
CCDS: CCDS26933.1

全选

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研究热度

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