| Type | Description |
|---|---|
| Definition | palmitoyl-protein thioesterase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-31 13:18:00 | Mice deficient in the lysosomal enzyme palmitoyl-protein thioesterase 1 (PPT1) display a complex retinal phenotype. | 31578378 |
| 2020-06-20 11:18:00 | PPT1 affects sperm quality and male fertility through regulating lysosomal function and cholesterol metabolism in Sertoli cells. | 31134714 |
| 2020-06-13 11:40:00 | PPT1 acts as a molecular rheostat that allows Conventional type 1 dendritic cells to crossprime efficiently without compromising viral resistance. | 31262842 |
| 2020-02-29 10:16:00 | The authors demonstrate that the developmental N-methyl-D-aspartate receptor (NMDAR) subunit switch from GluN2B to GluN2A is stagnated in Ppt1(-/-) mice. Correspondingly, Ppt1(-/-) neurons exhibit immature evoked NMDAR currents and dendritic spine morphology in vivo. | 30946007 |
| 2019-06-08 12:13:00 | Thes findings of this stuidy suggest that both Ppt1(-/-) microglia and astrocytes are dysfunctional and may contribute to the neurodegeneration observed in infantile neuronal ceroid lipofuscinosis disease | 30089511 |
| Type | IDs |
|---|---|
| Synonymous | 9530043G02Rik, AA960502, C77813, CLN1, D4Ertd184e, INCL, PPT |
| Gene |
UniProtKB-ID:
PPT1_MOUSE,
Q3U6J9_MOUSE,
Q3U6W3_MOUSE,
Q3TEL0_MOUSE
UniprotKB:
O88531,
Q3U6J9,
Q3U6W3,
Q3TEL0
UniParc:
UPI0000022F64,
UPI00005ACA9F,
UPI00005B259F
EMBL:
AK152940,
AK169579,
AF087568,
AK151107,
AK153106,
AK014561,
AF071025,
AK152474
Ensembl:
ENSMUSG00000028657
KO:
mmu:19063
|
| Nucleutide sequences |
EMBL-CDS:
AAD25224.1,
AAC25398.1,
BAE31725.1,
BAE31248.1,
BAE30117.1,
BAE31611.1,
BAE41238.1
Ensembl_TRS:
ENSMUST00000030412
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000030412
RefSeq:
NP_032943.2
|
| Others |
UniRef100:
UniRef100_Q3TEL0,
UniRef100_O88531,
UniRef100_Q3U6W3
UniRef90:
UniRef90_O88531,
UniRef90_Q3TEL0
UniRef50:
UniRef50_O88531,
UniRef50_H9G9T7
UniGene:
Mm.277719
CCDS:
CCDS38870.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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