| Type | Description |
|---|---|
| Definition | protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type II) |
| Date | Results | Publications |
|---|---|---|
| 2017-11-25 15:58:00 | surgical-induced Osteoarthritis mice treated with a miR-146a inhibitor significantly alleviated the destruction of articular cartilage via targeting Camk2d and Ppp3r2. | 28383548 |
| 2016-04-02 11:20:00 | this stusy demonstrates that male mice lacking Ppp3cc or Ppp3r2 genes (knockout mice) are infertile, with reduced sperm motility owing to an inflexible midpiece. | 26429887 |
| 2012-04-21 11:29:00 | we report that calcineurin subunit B interacted with TLR4, which in turn led to phosphorylaiton of IRF3 and secretion of IFN-beta | 22118374 |
| 2012-01-07 12:46:00 | The CnB could be of use as a prophylactic adjuvant as it is a human-derived safe agent and has immune-modulating effects that promote the control of cancer and infectious diseases. | 21447603 |
| 2010-01-21 00:00:00 | Deactivation of calcineurin/NFAT pathway-induced pathological hypertrophy is a preferential mechanism by which exercise training leads to the cardiac anti-remodelling effect in heart failure. | 19505981 |
| Type | IDs |
|---|---|
| Synonymous | CaNB2, CnB2 |
| Gene |
UniProtKB-ID:
CANB2_MOUSE,
Q497S1_MOUSE
UniprotKB:
Q63811,
Q497S1
UniParc:
UPI0000003F9C
EMBL:
AK029998,
BC100409,
AK161263,
AK132760,
S43865
Ensembl:
ENSMUSG00000028310
KO:
mmu:19059
|
| Nucleutide sequences |
EMBL-CDS:
AAB23172.1,
BAC26725.1,
BAE36277.1,
BAE21341.1,
AAI00410.1
Ensembl_TRS:
ENSMUST00000029991
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000029991
RefSeq:
NP_001004025.1
|
| Others |
UniRef100:
UniRef100_Q63811
UniRef90:
UniRef90_Q63811
UniRef50:
UniRef50_Q63811
UniGene:
Mm.46125
CCDS:
CCDS18179.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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