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19045 Ppp1ca

19045

Ppp1ca

protein phosphatase 1 catalytic subunit alpha

protein-coding

Mus musculus

基因描述

Type Description
Definition protein phosphatase 1 catalytic subunit alpha

研究结论

Date Results Publications
2018-02-24 10:26:00 These findings describe an original mechanism involving a phosphatase in the regulation of aldosterone signaling and provide new and important insights into the molecular mechanism underlying the MR turnover. 28454724
2017-08-26 13:11:00 Data, including data from studies using transgenic/knockout mice, suggest that Ppp1ca and Gnb1 interact in quiescent platelets; then, Ppp1ca and Plcb3 interact during platelet aggregation; thus, Gnb1 enlists Ppp1ca to modulate G protein-coupled receptor signaling. (Ppp1ca = protein phosphatase 1, catalytic subunit alpha; Gnb1 = guanine nucleotide-binding protein, subunit beta-1; Plcb3 = phospholipase C, subunit beta-3) 28615442
2014-05-24 10:08:00 Ang IV functions via regulating the activity of PP1 23744339
2012-12-22 10:09:00 Cell surface expression of the major amyloid-beta peptide (Abeta)-degrading enzyme, neprilysin, depends on phosphorylation by mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK) and dephosphorylation by protein phosphatase 1a. 22767595
2012-11-17 10:24:00 analysis of selective regulation of NR2B by protein phosphatase-1 for the control of the NMDA receptor in neuroprotection 22479519

名称对应

Type IDs
Synonymous Ppp1c, dism2
Gene
UniProtKB-ID: PP1A_MOUSE
UniprotKB: P62137
UniParc: UPI00000262E8
EMBL: AK159575, AK153517, AK090070, AK167538, AK028392, AK152667, AK167244, AK007932, AK151582, AK167880, AK167981, BC014828, U25809
Ensembl: ENSMUSG00000040385, ENSMUSG00000096994
KO: mmu:19045
Nucleutide sequences
EMBL-CDS: BAB25358.1, BAE39893.1, AAH14828.1, BAC41078.1, BAE35196.1, BAC25928.1, BAE39973.1, BAE39605.1, BAE39365.1, BAE31402.1, BAE32060.1, AAC99814.1, BAE30522.1
Ensembl_TRS: ENSMUST00000180575, ENSMUST00000046094
Protein sequencees
Ensembl_PRO: ENSMUSP00000137997, ENSMUSP00000039109
RefSeq: NP_114074.1
Others
UniRef100: UniRef100_P62137
UniRef90: UniRef90_P62137
UniRef50: UniRef50_P62137
UniGene: Mm.1970, Mm.474260
CCDS: CCDS29421.1

全选

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