| Type | Description |
|---|---|
| Definition | protein phosphatase 1A, magnesium dependent, alpha isoform |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:26:00 | PPM1A Controls Diabetic Gene Programming through Directly Dephosphorylating PPARgamma at Ser273. | 32024237 |
| 2020-09-05 13:53:00 | Protein phosphatase magnesium-dependent 1A induces inflammation in rheumatoid arthritis. | 31791585 |
| 2018-06-16 12:02:00 | VRK1 self-represses its activity to phosphorylate PXR through cyclin-dependent kinase 2 (CDK2) in high glucose conditions, resulting in the repression of the PCK1 gene. This PXR phosphorylation was also observed in fasting mouse livers. Thus, the VRK1-CDK2-PXR-PP2Calpha-SGK2 pathway can be a novel physiological cell signaling that regulates gluconeogenesis in response to glucose. | 28911860 |
| 2016-02-13 11:05:00 | findings demonstrate a novel regulatory circuit in which STING and TBK1 reciprocally regulate each other to enable efficient antiviral signaling activation, and PPM1A dephosphorylates STING and TBK1 | 25815785 |
| 2015-07-25 10:40:00 | the studies presented here position PPM1A as a new player in the wound healing-inflammation-angiogenesis axis in mouse, reveal its crucial role in homeostasis on injury, and highlight its potential as a therapeutic mediator in pathologic conditions | 25196308 |
| Type | IDs |
|---|---|
| Synonymous | 2310003C21Rik, 2900017D14Rik, AI427932, AU017636, MMPa-2, MPPa-1 |
| Gene |
UniProtKB-ID:
PPM1A_MOUSE,
Q9EQE3_MOUSE
UniprotKB:
P49443,
Q9EQE3
UniParc:
UPI00000018C6,
UPI00000E884F
EMBL:
AK076054,
AF259672,
BC008595,
D28117
Ensembl:
ENSMUSG00000021096
KO:
mmu:19042
|
| Nucleutide sequences |
EMBL-CDS:
BAA05662.1,
AAH08595.1,
AAG44661.1,
BAC36151.1
Ensembl_TRS:
ENSMUST00000021514
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000021514
RefSeq:
XP_036013149.1,
XP_036013148.1,
NP_032936.1
|
| Others |
UniRef100:
UniRef100_Q9EQE3,
UniRef100_P49443
UniRef90:
UniRef90_P49443,
UniRef90_K7GC17
UniRef50:
UniRef50_P35813
UniGene:
Mm.261045
CCDS:
CCDS25970.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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