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19025 Ctsa

19025

Ctsa

cathepsin A

protein-coding

Mus musculus

基因描述

Type Description
Definition cathepsin A

研究结论

Date Results Publications
2021-02-02 13:26:00 Cathepsin A contributes to left ventricular remodeling by degrading extracellular superoxide dismutase in mice. 32647007
2017-09-09 11:33:00 in normal tissues the tandem of serine carboxypeptidases, Scpep1 and CathA likely constitutes an important part of the physiological mechanism responsible for the balanced elimination of heightened levels of ET-1 that otherwise would accumulate in tissues and consequently contribute to development of the hyper-proliferative corneal dystrophy and abnormal skin thickening 28234994
2014-12-20 12:52:00 our results define the biological role of mammalian serine carboxypeptidase Scpep1 and suggest that Scpep1 and CathA together participate in the control of ET-1 regulation of vascular tone and hemodynamics 24586188
2013-08-31 12:36:00 Loss of the cathepsin A results in the lysosomal storage disease galactosialidosis. However, mice with a catalytically inactive cathepsin A enzyme show no signs of this disease. 23495688
2013-01-17 15:30:00 characterization of human PPCA, including N-terminal sequencing of the two cleavage products 3136930

名称对应

Type IDs
Synonymous AU019505, PPCA, Ppgb
Gene
UniProtKB-ID: PPGB_MOUSE, Q544R6_MOUSE, G3X8T3_MOUSE, Q9D2D1_MOUSE
UniprotKB: P16675, Q544R6, G3X8T3, Q9D2D1
UniParc: UPI0000003FBF, UPI00000E8ACE, UPI00001EE59F
EMBL: J05261, AK159150, AK032197, AL591495, AK159766, BC018534, AK019861
Ensembl: ENSMUSG00000017760
KO: mmu:19025
Nucleutide sequences
EMBL-CDS: AAA39982.1, AAH18534.1, BAC27752.1, BAE35356.1, BAE34857.1, BAB31888.1
Ensembl_TRS: ENSMUST00000103093, ENSMUST00000103092
Protein sequencees
Ensembl_PRO: ENSMUSP00000099382, ENSMUSP00000099381
RefSeq: NP_032932.2, XP_030104427.1, NP_001033581.1
Others
UniRef100: UniRef100_Q9D2D1, UniRef100_P16675
UniRef90: UniRef90_P16675
UniRef50: UniRef50_P16675
UniGene: Mm.359633, Mm.474586
CCDS: CCDS17062.1

全选

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