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1902 LPAR1

1902

LPAR1

lysophosphatidic acid receptor 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition lysophosphatidic acid receptor 1

研究结论

Date Results Publications
2020-01-11 12:40:00 LPA1 receptor activation induces nuclear translocation in glioblastoma cells 30849522
2019-11-30 11:58:00 It is a tumor suppressor gene. 30395690
2019-10-05 12:17:00 findings suggest an LPA1 receptor-dependent pathway by which LPA increases arteriolar release of mitochondria-derived hydrogen peroxide as a mediator of flow-induced dilation 30153326
2019-08-03 11:50:00 his study uncovers an LPA1-EGFR signaling axis that is used for cell invasion in hypoxia and suggests a potential target to impede cancer metastasis 29866927
2019-03-30 13:11:00 mRNA expression analyses revealed that ADSCs and MES largely expressed LPA receptor 1 (LPAR1) while epithelial cells mainly expressed LPAR6. LPA 18:1 activated all the cell populations and cell lines by rise in cytosolic free calcium concentrations. MES and ADSCs expressed ATX whereas epithelial cells did not. 30567518

名称对应

Type IDs
Synonymous EDG2, GPR26, Gpcr26, LPA1, Mrec1.3, VZG1, edg-2, rec.1.3, vzg-1
Gene
UniProtKB-ID: LPAR1_HUMAN, Q5VZX0_HUMAN
UniprotKB: Q92633, Q5VZX0
UniParc: UPI000011DBF9, UPI00017A7213
EMBL: AL442064, AY322546, AL157881, BC030615, Y09479, BC036034, U78192, AK296374, U80811, AK022808, CH471105, AC007157, AK290287
Ensembl: ENSG00000198121
KO: hsa:1902
Nucleutide sequences
EMBL-CDS: AAC51139.1, AAH30615.1, CAA70686.1, AAH36034.1, AAC00530.1, AAP84359.1, CAA70687.1, BAG59048.1, EAW59069.1, BAG51118.1, BAF82976.1, EAW59068.1
Gene_ORFName: hCG_27597
Ensembl_TRS: ENST00000374430, ENST00000374431, ENST00000358883
Protein sequencees
Ensembl_PRO: ENSP00000363552, ENSP00000351755, ENSP00000363553
RefSeq: NP_001374448.1, NP_001374412.1, NP_001374432.1, NP_001374442.1, NP_001374440.1, NP_001374431.1, NP_001374408.1, NP_001374406.1, NP_001338346.1, NP_001374403.1, NP_001374416.1, NP_001374425.1, NP_001338347.1, NP_001338329.1, NP_001338335.1, NP_001338340.1, NP_001338328.1, NP_001338345.1, NP_001338348.1, NP_001374449.1, NP_001374418.1, NP_001374413.1, NP_001374407.1, NP_001374415.1, NP_001338333.1, NP_001338338.1, NP_001374423.1, NP_001338342.1, NP_001374435.1, NP_001374411.1, NP_001338332.1, NP_001338330.1, NP_001374444.1, NP_001374445.1, NP_001374424.1, NP_001374417.1, NP_001374437.1, NP_001374399.1, NP_001338326.1, NP_001374430.1, NP_001374450.1, NP_001374434.1, NP_001374436.1, NP_001374443.1, NP_001338334.1, NP_001374446.1, NP_001374401.1, NP_001338343.1, NP_001374439.1, NP_001338331.1, NP_476500.1, NP_001338344.1, NP_001374427.1, NP_001374400.1, NP_001374447.1, NP_001374419.1, NP_001374404.1, NP_001374405.1, NP_001338341.1, NP_001338327.1, NP_001374420.1, NP_001338349.1, NP_001392.2, NP_001374402.1, NP_001338337.1, NP_001374441.1, XP_005251839.1, NP_001374414.1, NP_001374426.1, NP_001374433.1, NP_001374409.1, NP_001338336.1, NP_001374422.1, NP_001338339.1, NP_001374438.1, NP_001374421.1, NP_001374410.1
Others
UniRef100: UniRef100_Q92633
UniRef90: UniRef90_Q92633
UniRef50: UniRef50_Q92633
UniGene: Hs.126667
CCDS: CCDS6777.1

全选

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