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18998 Pou4f3

18998

Pou4f3

POU domain, class 4, transcription factor 3

protein-coding

Mus musculus

基因描述

Type Description
Definition POU domain, class 4, transcription factor 3

研究结论

Date Results Publications
2020-12-12 13:29:00 Aldh inhibitor restores auditory function in a mouse model of human deafness. 32970669
2018-05-19 10:43:00 identify separate enhancers at various locations of pou4f3 gene that direct expression to different inner ear hair cells types at different ages and determine that 0.4 kb of upstream sequence determines expression level 27592349
2018-02-24 11:10:00 Atoh1 function in hair cell differentiation is modulated by interaction with other transcription factors, such as Gfi1 and Pou4f3. (Review) 27751776
2017-05-06 16:05:00 These data illuminate a genetic pathway that initiates auditory HC regeneration and suggest p27(Kip1), GATA3, and POU4F3 as additional therapeutic targets for ATOH1-mediated auditory hair cells regeneration. 28402854
2015-11-28 11:23:00 These data demonstrate that Nr2f2 is a direct target of POU4F3 in vitro and that this regulatory relationship may be relevant to hair cell development and survival. 25372459

名称对应

Type IDs
Synonymous Brn3.1, Brn3c, ddl, dreidel
Gene
UniProtKB-ID: PO4F3_MOUSE
UniprotKB: Q63955
UniParc: UPI00004CB3BD
EMBL: S69352, BC145941, CH466528
Ensembl: ENSMUSG00000024497
KO: mmu:18998
Nucleutide sequences
EMBL-CDS: AAI45942.1, EDL10035.1, AAB30579.1
Ensembl_TRS: ENSMUST00000025374
Protein sequencees
Ensembl_PRO: ENSMUSP00000025374
RefSeq: NP_620395.2
Others
UniRef100: UniRef100_Q63955
UniRef90: UniRef90_Q15319
UniRef50: UniRef50_Q15319
UniGene: Mm.488204
CCDS: CCDS29212.1

全选

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研究热度

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