| Type | Description |
|---|---|
| Definition | POU domain, class 3, transcription factor 3 |
| Date | Results | Publications |
|---|---|---|
| 2017-07-22 11:16:00 | The results of the present study confirm the important function of POU3F3 in nephron patterning, especially in development of the the Thick Ascending Limb of the Loop of Henle. Missense Mutation of POU Domain Class 3 3 in Pou3f3L423P Mice Causes Reduced Nephron Number and Impaired Development of the Thick Ascending Limb of the Loop of Henle. | 27420727 |
| 2016-09-10 10:48:00 | results suggest that a mutually repressive mechanism exists between Brn1/2 and Rorb expression and that the established expression of Brn1/2 and Rorb further specifies those neurons into L2/3 and L4, respectively, during UCP maturation | 26951672 |
| 2016-08-06 11:17:00 | Line Pou3f3L423P is a viable mouse model harboring a homozygous Pou3f3 mutation. | 27003440 |
| 2015-08-18 12:21:00 | Brn1 predominantly forms homomdimers on MORE cis elements in NS5 mouse neural stem cells | 26265007 |
| 2014-08-16 10:50:00 | Onset of Pou3f3 expression occurs in ventricular zone progenitors, and that Pou3f3 subsequently label neural progeny switching from deep-layer Ctip2+ identity to Satb2+ upper-layer fate as they migrate to proper superficial positions. | 22892427 |
| Type | IDs |
|---|---|
| Synonymous | Brn-1, Brn1, HST011, Otf8, Skin1, urehr2 |
| Gene |
UniProtKB-ID:
PO3F3_MOUSE
UniprotKB:
P31361
UniParc:
UPI0000194ED9
EMBL:
M88299,
AC122898
Ensembl:
ENSMUSG00000045515
KO:
mmu:18993
|
| Nucleutide sequences |
EMBL-CDS:
AAA39960.1
Ensembl_TRS:
ENSMUST00000054883,
ENSMUST00000239323
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000159226,
ENSMUSP00000052088
RefSeq:
NP_032926.2
|
| Others |
UniRef100:
UniRef100_P31361
UniRef90:
UniRef90_P31361
UniRef50:
UniRef50_P31361
UniGene:
Mm.489878
CCDS:
CCDS14917.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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