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18986 Pou2f1

18986

Pou2f1

POU domain, class 2, transcription factor 1

protein-coding

Mus musculus

基因描述

Type Description
Definition POU domain, class 2, transcription factor 1

研究结论

Date Results Publications
2021-04-13 10:07:00 Pou2f1 and Pou2f2 cooperate to control the timing of cone photoreceptor production in the developing mouse retina. 32878923
2020-02-22 10:18:00 In MLL-AF9-driven mouse models, partial loss of Oct1 protects from myeloid leukemia. Complete Oct1 loss completely suppresses leukemia but results in lethality from bone marrow failure. Loss of Oct1 in normal hematopoietic transplants results in superficially normal long-term reconstitution; however, animals become acutely sensitive to 5-fluorouracil, indicating that Oct1 is dispensable for normal hematopoiesis. 31295506
2020-01-11 10:50:00 Oct1-deficient T cells mitigated reduced infiltrating T cells and cytokine production in an autoimmune neuroinflammation disease model. 31266507
2019-12-07 10:45:00 Oct1 is selectively required for colon regeneration and regulates colon malignancy. 31059499
2019-06-29 11:53:00 This findings of this study indicated that OCT1 may participate in neuropathic pain at least in part by transcriptionally activating Dnmt3a and subsequently epigenetic silencing of Oprm1 and Kcan2 in the DRG. 30247265

名称对应

Type IDs
Synonymous 2810482H01Rik, NF-A1, Oct-1, Oct1, Otf-1, Otf1
Gene
UniProtKB-ID: PO2F1_MOUSE, F8VQL7_MOUSE, E9Q6Z8_MOUSE, A0A0R4J1Z4_MOUSE
UniprotKB: P25425, F8VQL7, E9Q6Z8, A0A0R4J1Z4
UniParc: UPI0000191DF5, UPI00004F6F0F, UPI00004F6F10, UPI00000E6890, UPI0000191DF8, UPI00002259A3, UPI0000191DF4, UPI00000EAC1B, UPI00004346C5, UPI00001EDE34, UPI0000021359, UPI0000191DF7, UPI0000191DF9, UPI0000191DF6, UPI0000191DF3
EMBL: AJ489474, X68362, X70325, X70324, AJ296212, AY177625, X56230, AF095459, X51958, X68364, AF095460, AF508939, AK028237, AF095458, S65461, X68363, AC093371
Ensembl: ENSMUSG00000026565
KO: mmu:18986
Nucleutide sequences
EMBL-CDS: AAD25327.1, BAC25832.1, AAO45298.1, AAD25326.1, CAA48423.1, CAA49791.1, CAA39679.1, CAC34943.1, AAD25325.1, AAM34281.1, AAB28234.1, CAD35743.1, CAA49792.1, CAA48424.1, CAA36217.1, CAA48422.1
Ensembl_TRS: ENSMUST00000184643, ENSMUST00000111429, ENSMUST00000069609, ENSMUST00000111427, ENSMUST00000160908, ENSMUST00000160260
Protein sequencees
Ensembl_PRO: ENSMUSP00000138962, ENSMUSP00000107057, ENSMUSP00000064000, ENSMUSP00000107056, ENSMUSP00000125444, ENSMUSP00000124738
RefSeq: NP_945150.2, NP_945151.2, XP_006496767.1, XP_036018678.1, NP_001355737.1, NP_945152.2, XP_030108147.1, XP_030108146.1, XP_017174849.1, NP_035267.2
Others
UniRef100: UniRef100_F8VQL7, UniRef100_P25425, UniRef100_E9Q6Z8
UniRef90: UniRef90_P25425-5, UniRef90_P25425
UniRef50: UniRef50_P25425-5, UniRef50_P14859
UniGene: Mm.245261
CCDS: CCDS15444.1

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研究热度

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