| Type | Description |
|---|---|
| Definition | POU domain, class 2, associating factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 10:19:00 | The Bob1 enhances IL-17A expression in vivo and in vitro by interacting with RORgammat in Th17cells, suggesting that Bob1 plays a pivotal role in Th17-mediated autoimmune disease. | 31103264 |
| 2020-07-25 10:13:00 | Our findings demonstrate a novel role for BOB.1 in B cells during TD GC responses and suggest that its dysregulation may contribute to the pathogenesis of RA by disturbing the B cell-fate determination. | 31053401 |
| 2018-08-18 11:26:00 | The number of follicular B2 lymphocytes and expression of the B-cell-specific transcriptional coactivator OcaB increase with age in spleen and in intra-abdominal epididymal white adipose tissue (eWAT), concomitantly with higher circulating levels of IgG and impaired glucose homeostasis. | 29496744 |
| 2016-09-10 11:23:00 | Bob1 promotes the development of follicular T helper cells via Bcl6.Bob1 is directly involved in follicular T helper cell differentiation and required for mounting normal T cell-dependent B-cell responses. | 26957522 |
| 2016-04-16 11:33:00 | Findings indicate octamer transcription factor-1 (Oct1) and Oct binding factor 1 protein (OCA-B) as central mediators of CD4(+) T cell memory. | 26481684 |
| Type | IDs |
|---|---|
| Synonymous | BOB.1, Bob-1, Bob1, OBF-1, OBF.1, OCA-B, OCAB |
| Gene |
UniProtKB-ID:
OBF1_MOUSE,
Q542H4_MOUSE
UniprotKB:
Q64693,
Q542H4
UniParc:
UPI00000041B0
EMBL:
Z54283,
AK135080,
AK088587,
U43788
Ensembl:
ENSMUSG00000032053
KO:
mmu:18985
|
| Nucleutide sequences |
EMBL-CDS:
AAC52618.1,
CAA91058.1,
BAC40437.1,
BAE22412.1
Ensembl_TRS:
ENSMUST00000034554
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000034554
RefSeq:
NP_035266.1
|
| Others |
UniRef100:
UniRef100_Q64693
UniRef90:
UniRef90_Q64693
UniRef50:
UniRef50_Q16633
UniGene:
Mm.897
CCDS:
CCDS23176.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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