| Type | Description |
|---|---|
| Definition | P450 (cytochrome) oxidoreductase |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:51:00 | Membrane Damage during Ferroptosis Is Caused by Oxidation of Phospholipids Catalyzed by the Oxidoreductases POR and CYB5R1. | 33321093 |
| 2019-11-02 13:25:00 | Hepatic cytochrome b5/P450 reductase contribute to the bioactivation of ellipticine in vitro, but not in vivo. | 30685480 |
| 2017-12-16 12:12:00 | Knockout of the cytochrome P450 reductase by CRISPR/Cas9 technology (POR(-/-)) in HEK293 cells overexpressing Nox4 or Nox5 did not interfere with production in intact cells. However, POR(-/-) abolished the signal in NADPH-stimulated assays using membrane fractions from the very same cells. Moreover, membranes of rat smooth muscle cells treated with angiotensin II showed an increased NADPH-dependent signal with lucigen | 27863990 |
| 2016-12-31 10:10:00 | we observed that miR-378 modulates the oscillation amplitudes of Cdkn1a in the control of cell cycle and Por in the regulation of oxidation reduction by forming partnership with different circadian transcription factors | 26898952 |
| 2015-04-11 11:53:00 | Results are the first to show that some forms of opioid-mediated stress-induced analgesia require brain neuronal P450 activity. | 25020125 |
| Type | IDs |
|---|---|
| Synonymous | 4933424M13Rik, CPR, CYPOR, P450R |
| Gene |
UniProtKB-ID:
NCPR_MOUSE
UniprotKB:
P37040
UniParc:
UPI0000001A89
EMBL:
BC031463,
D17571
Ensembl:
ENSMUSG00000005514
KO:
mmu:18984
|
| Nucleutide sequences |
EMBL-CDS:
BAA04496.1,
AAH31463.1
Ensembl_TRS:
ENSMUST00000005651
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000005651
RefSeq:
XP_006504461.1,
NP_032924.1,
XP_036020784.1,
XP_006504462.1
|
| Others |
UniRef100:
UniRef100_P37040
UniRef90:
UniRef90_P00388
UniRef50:
UniRef50_P00388
UniGene:
Mm.3863
CCDS:
CCDS39318.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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