| Type | Description |
|---|---|
| Definition | polymerase (DNA directed), gamma |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:23:00 | Mitochondrial dysfunction impairs osteogenesis, increases osteoclast activity, and accelerates age related bone loss. | 32669663 |
| 2020-07-18 12:07:00 | 17-month-old Polg(mut/mut) mice displayed a profound loss of spiral ganglion neurons in the cochlea. | 31344454 |
| 2019-03-02 12:37:00 | CR benefits oocyte quality and fertility outcomes in naturally aged female mice, it does not sufficiently improve oocyte quality in PolgD257A/D257A | 30240410 |
| 2019-02-02 10:46:00 | mtDNA maintenance is regulated by a non-coding genomic complex driving POLG expression in specific neuronal populations. | 29109127 |
| 2019-01-12 11:04:00 | Study found that the exonuclease function of the mtDNA polymerase gamma (POLG) is required for this rapid degradation of mtDNA fragments. POLG is recruited to linearized DNA fragments in an origin of replication-independent manner. | 29950568 |
| Type | IDs |
|---|---|
| Synonymous | AA409516, PolgA |
| Gene |
UniProtKB-ID:
Q3UZX3_MOUSE,
Q75WC0_MOUSE,
Q3UG70_MOUSE
UniprotKB:
Q3UZX3,
Q75WC0,
Q3UG70
UniParc:
UPI00005AC752,
UPI00005AB9B5,
UPI00001D6A90
EMBL:
AK148091,
AC110909,
AK133584,
AB121698
Ensembl:
ENSMUSG00000039176
|
| Nucleutide sequences |
EMBL-CDS:
BAE21732.1,
BAC98463.1,
BAE28339.1
Ensembl_TRS:
ENSMUST00000073889
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000073551
RefSeq:
XP_006540774.1,
NP_001347025.1,
NP_001347024.1,
XP_030098081.1,
XP_006540771.1,
NP_059490.2,
XP_036008683.1
|
| Others |
UniRef100:
UniRef100_Q3UG70,
UniRef100_Q3UZX3,
UniRef100_Q75WC0
UniRef90:
UniRef90_Q9QYV8
UniRef50:
UniRef50_P54098
UniGene:
Mm.3616
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| 1 |
Karolinska Institutet |
14 |
| 2 |
Max Planck Institute for Biology of Ageing |
8 |
| 3 |
University of Wisconsin |
5 |
| 4 |
University of Washington |
4 |
| 5 |
University of Miami Miller School of Medicine |
4 |
| 排名 | 研究人员 | 文献 |
|---|---|---|
| 1 |
Tomas A Prolla |
18 |
| 2 |
Nils-Göran Larsson |
16 |
| 3 |
Gregory C Kujoth |
11 |
| 4 |
Aleksandra Trifunovic |
10 |
| 5 |
James B Stewart |
8 |