| Type | Description |
|---|---|
| Definition | thymidine phosphorylase |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:53:00 | Thymidine phosphorylase promotes angiogenesis and tumour growth in intrahepatic cholangiocarcinoma. | 32476180 |
| 2020-03-14 10:11:00 | These results indicated that hDHFR is not the only target of Pyr. We further found that thymidine phosphorylase (TP), an enzyme that is closely associated with the EMT of cancer cells, is also a target protein of Pyr. The data retrieved from the Cancer Genome Atlas (TCGA) database revealed that TP overexpression is associated with poor prognosis of patients with lung cancer | 30642883 |
| 2020-01-11 12:40:00 | Kinetics mechanism and regulation of native human hepatic thymidine phosphorylase | 30849523 |
| 2019-08-10 12:36:00 | Sp1-binding sites in the TP promoter were methylated in epidermoid carcinoma. 5-Aza-CdR demethylated Sp1-binding sites and enhanced sensitivity to 5-FU | 31366497 |
| 2018-01-13 12:38:00 | Data show that thymidine phosphorylase (TYMP) positive patients had higher systemic immune-inflammation index (SII) score. | 27283904 |
| Type | IDs |
|---|---|
| Synonymous | ECGF, ECGF1, MEDPS1, MNGIE, MTDPS1, PDECGF, TP, hPD-ECGF |
| Gene |
UniProtKB-ID:
TYPH_HUMAN,
B2RBL3_HUMAN,
E5KRG5_HUMAN
UniprotKB:
P19971,
B2RBL3,
E5KRG5
UniParc:
UPI000013CD32,
UPI000175086C,
UPI000155D5D9
EMBL:
HQ205681,
HQ205689,
HQ205698,
HQ205678,
HQ205691,
HQ205668,
HQ205696,
HQ205683,
HQ205674,
CH471138,
HQ205672,
HQ205703,
M63193,
HQ205671,
HQ205695,
AK225269,
HQ205694,
HQ205677,
HQ205700,
HQ205675,
HQ205669,
HQ205692,
HQ205699,
HQ205666,
HQ205684,
BC018160,
HQ205690,
HQ205701,
AK314716,
HQ205697,
HQ205686,
HQ205687,
HQ205673,
HQ205705,
HQ205670,
HQ205688,
KU178037,
HQ205704,
HQ205667,
HQ205702,
HQ205682,
HQ205693,
HQ205676,
BC052211,
HQ205685,
HQ205679,
U62317,
HQ205680
Ensembl:
ENSG00000025708
KO:
hsa:1890
|
| Nucleutide sequences |
EMBL-CDS:
AAB03344.2,
AAH18160.1,
AAA60043.1,
AAH52211.1,
BAG37260.1,
ALQ33495.1,
ADP91526.1,
ADP91508.1,
ADP91495.1,
ADP91523.1,
ADP91522.1,
EAW73564.1,
ADP91500.1,
ADP91530.1,
EAW73561.1,
ADP91532.1,
ADP91513.1,
ADP91505.1,
ADP91503.1,
ADP91528.1,
ADP91507.1,
ADP91497.1,
ADP91515.1,
ADP91516.1,
ADP91496.1,
ADP91512.1,
ADP91529.1,
ADP91533.1,
ADP91531.1,
ADP91498.1,
EAW73562.1,
ADP91501.1,
ADP91504.1,
ADP91509.1,
ADP91519.1,
EAW73560.1,
ADP91524.1,
ADP91510.1,
ADP91494.1,
ADP91518.1,
ADP91506.1,
ADP91502.1,
ADP91499.1,
ADP91527.1,
EAW73563.1,
ADP91520.1,
ADP91511.1,
ADP91514.1,
ADP91521.1,
ADP91525.1,
ADP91517.1
Gene_ORFName:
hCG_1988078
Ensembl_TRS:
ENST00000395678,
ENST00000487577,
ENST00000395681,
ENST00000395680,
ENST00000252029
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000379037,
ENSP00000498844,
ENSP00000379038,
ENSP00000379036,
ENSP00000252029
RefSeq:
NP_001244917.1,
NP_001107228.1,
NP_001944.1,
NP_001244918.1,
NP_001107227.1
|
| Others |
UniRef100:
UniRef100_P19971,
UniRef100_B2RBL3
UniRef90:
UniRef90_P19971
UniRef50:
UniRef50_P19971
UniGene:
Hs.180903
CCDS:
CCDS14096.1,
CCDS58811.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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Ensembl: {{protein.proteinEnsembl}} |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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