| Type | Description |
|---|---|
| Definition | alanine--glyoxylate and serine--pyruvate aminotransferase |
| Date | Results | Publications |
|---|---|---|
| 2020-09-19 16:27:00 | Loss of alanine-glyoxylate and serine-pyruvate aminotransferase expression accelerated the progression of hepatocellular carcinoma and predicted poor prognosis. | 31771612 |
| 2020-07-25 10:54:00 | two human constructs, wild-type and engineered AGT (RHEAM), were tested in Agxt(-/-) mice. Repeat dosing in Agxt(-/-) mice resulted in a 40% reduction in urinary oxalate, suggesting therapeutic benefit. | 30676254 |
| 2020-07-11 12:37:00 | novel mutation c. 799A>T p. (IIe267Phe) detected in primary hyperoxaluria type 1 patient and family | 32569165 |
| 2020-01-11 12:40:00 | Expression of the primary hyperoxaluria type 1-causal gene AGXT can be regulated at the posttranscriptional level by miR-4660. | 30852714 |
| 2019-10-26 10:12:00 | The most common AGXT gene mutation found in Libyan children with primary hyperoxaluria type 1 was c.731T>C (p.lle244thr) and this is more likely due to the strong genetic pooling caused by the high consanguinity rate. | 29456205 |
| Type | IDs |
|---|---|
| Synonymous | AGT, AGT1, AGXT1, PH1, SPAT, SPT, TLH6 |
| Gene |
UniProtKB-ID:
SPYA_HUMAN
UniprotKB:
P21549
UniParc:
UPI0000135E9B
EMBL:
CH471063,
AC104809,
X53414,
D13368,
BC132819,
M61763,
X56092,
AK292754
Ensembl:
ENSG00000172482
KO:
hsa:189
|
| Nucleutide sequences |
EMBL-CDS:
AAA51680.1,
CAA39572.1,
CAA37493.1,
BAA02632.1,
BAF85443.1,
EAW71222.1,
AAY24168.1,
AAI32820.1
Ensembl_TRS:
ENST00000307503
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000302620
RefSeq:
NP_000021.1
|
| Others |
UniRef100:
UniRef100_P21549
UniRef90:
UniRef90_P21549
UniRef50:
UniRef50_P21549
UniGene:
Hs.144567
CCDS:
CCDS2543.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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