| Type | Description |
|---|---|
| Definition | PMS1 homolog2, mismatch repair system component |
| Date | Results | Publications |
|---|---|---|
| 2017-08-19 11:52:00 | Pms2/Mlh1 and multiple uracil glycosylases act jointly, each one with a distinct strand bias, to enlarge the immunoglobulin gene mutation spectrum from G-C to A-T bases. | 28283534 |
| 2016-10-29 10:06:00 | Primary function of Pms2 during spermatogenesis is to stabilize Mlh1 levels prior to its critical crossing over function with Mlh3. An intact Pms2 ATPase domain is not essential for male fertility. | 26753533 |
| 2013-05-04 11:21:00 | Pms2 specifically suppresses large expansions of a pathogenic trinucleotide repeat sequence in neuronal tissues, possibly acting independently of the canonical mismatch repair pathway. | 23071719 |
| 2012-05-05 10:50:00 | Down-regulation of PMS2 is associated with initiation and growth of neuroblastoma and brain tumour multicellular spheroids. | 22145025 |
| 2011-03-19 10:38:00 | the integrity of the MLH1 ATPase domain is more critical than the PMS2 ATPase domain for normal DNA mismatch repair functions | 20864418 |
| Type | IDs |
|---|---|
| Synonymous | AW555130, Pmsl2 |
| Gene |
UniProtKB-ID:
B9EJ22_MOUSE
UniprotKB:
B9EJ22
UniParc:
UPI0000478597
EMBL:
BC141287,
AC121917
Ensembl:
ENSMUSG00000079109
KO:
mmu:18861
|
| Nucleutide sequences |
EMBL-CDS:
AAI41288.1
Ensembl_TRS:
ENSMUST00000148011
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000119875
RefSeq:
XP_036020778.1,
XP_036020772.1,
XP_036020781.1,
XP_036020773.1,
XP_017176199.1,
XP_036020777.1,
XP_017176201.1,
XP_036020783.1,
XP_036020775.1,
XP_036020782.1,
XP_036020776.1,
XP_036020780.1,
XP_036020774.1,
XP_030110063.1,
XP_006504875.1,
XP_036020779.1,
XP_030110061.1,
NP_032912.2,
XP_030110064.1,
XP_030110062.1
|
| Others |
UniRef100:
UniRef100_B9EJ22
UniRef90:
UniRef90_P54279
UniRef50:
UniRef50_P54279
UniGene:
Mm.2950
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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