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18854 Pml

18854

Pml

promyelocytic leukemia

protein-coding

Mus musculus

基因描述

Type Description
Definition promyelocytic leukemia

研究结论

Date Results Publications
2020-03-28 10:44:00 we uncovered a novel reciprocal loop of TGF-beta1/PML SUMOylation/Pin1 leading to myocardial fibrosis. 30246389
2020-01-18 11:36:00 Loss of PML increases H3.3 deposition in subtelomeric, telomeric, pericentric and centromeric repeats in mouse embryonic fibroblasts, while other repeat classes are not affected. 30850162
2019-02-09 10:34:00 Pml Nuclear bodies (NB) are critical for DNA damage responses, and Pml NB disruption is a central contributor to Acute promyelocytic leukemia pathogenesis. 29191918
2018-05-26 11:24:00 PML mediates the binding of PER2 to BMAL1 in the BMAL1/CLOCK heterodimer and is an important component in the organization of a functional clock complex in the nucleus. 27383066
2018-03-10 10:56:00 Promyelocytic leukemia protein Pml -/- cells showed a higher proliferation rate, compared to Pml +/+ cells. 29302031

名称对应

Type IDs
Synonymous 1200009E24Rik, AI661194, Trim19
Gene
UniProtKB-ID: PML_MOUSE, Q8BSJ6_MOUSE, A0A068EW80_MOUSE, D3Z3A6_MOUSE
UniprotKB: Q60953, Q8BSJ6, A0A068EW80, D3Z3A6
UniParc: UPI000024F4F9, UPI00000EACAE, UPI0001889E0D, UPI0001526383
EMBL: KJ650238, AK032799, BC020990, U33626, AK028044, AC160976
Ensembl: ENSMUSG00000036986
KO: mmu:18854
Nucleutide sequences
EMBL-CDS: AAH20990.2, AAA97601.2, BAC25716.1, BAC28028.1, AID54412.1
Ensembl_TRS: ENSMUST00000114136, ENSMUST00000085673, ENSMUST00000135310
Protein sequencees
Ensembl_PRO: ENSMUSP00000109771, ENSMUSP00000082816, ENSMUSP00000122854
RefSeq: NP_835188.2, NP_001298017.1, XP_006510923.1, XP_006510925.1, XP_030099988.1, XP_006510924.1, NP_032910.3, XP_006510927.1, XP_017168701.1
Others
UniRef100: UniRef100_Q60953, UniRef100_D3Z3A6
UniRef90: UniRef90_Q60953, UniRef90_D3Z3A6
UniRef50: UniRef50_P29590, UniRef50_D3Z3A6
UniGene: Mm.392123
CCDS: CCDS23240.2, CCDS23239.1

全选

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