| Type | Description |
|---|---|
| Definition | BPI fold containing family A, member 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-28 11:41:00 | identify a novel role for Bpifa1 in the regulation of Cxcl10-mediated polymorphonuclear cell recruitment to the lungs via IFNgamma and -lambda signaling during acute inflammation | 30461288 |
| 2018-11-10 11:10:00 | Bpifa1-deficient (Bpifa1-/-) mice exhibited spontaneous airway hyperresponsiveness and that excised tracheas from Bpifa1+/+ but not Bpifa1-/- mice were capable of reducing airway smooth muscle contraction. | 28165446 |
| 2018-08-18 11:55:00 | this study shows that BPIFA1/SPLUNC1 restricts influenza A virus infection | 28513596 |
| 2018-07-21 12:16:00 | SPLUNC1-knockout mice was established in a LPS-induced acute lung injury (ALI) mouse model to study the anti-inflammatory effect of SPLUNC1. Results found that SPLUNC1 deficiency upregulated levels of ALI-related cytokines leading to more severe lung injury after LPS injection. Moreover, further data discovered that the presence of SPLUNC1 can suppress the recruitment of CD11b+Gr-1+ MDSCs to the spleen in LPS-induced ALI. | 29115527 |
| 2016-03-05 11:38:00 | Loss of Splunc1 predisposes mice to the development of otitis media. | 25765466 |
| Type | IDs |
|---|---|
| Synonymous | LUNX, NASG, Plunc, SPLUNC1, SPURT |
| Gene |
UniProtKB-ID:
BPIA1_MOUSE
UniprotKB:
P97361
UniParc:
UPI0000022BFA
EMBL:
AF356785,
BC054375,
U69172
Ensembl:
ENSMUSG00000027483
KO:
mmu:18843
|
| Nucleutide sequences |
EMBL-CDS:
AAB63256.1,
AAK63069.1,
AAH54375.1
Ensembl_TRS:
ENSMUST00000028985
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000028985
RefSeq:
NP_035256.2
|
| Others |
UniRef100:
UniRef100_P97361
UniRef90:
UniRef90_P97361
UniRef50:
UniRef50_P97361
UniGene:
Mm.268852
CCDS:
CCDS16925.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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