| Type | Description |
|---|---|
| Definition | phospholipid transfer protein |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 10:33:00 | Disruption of PLTP-mediated HDL maturation reduces SR-BI deficiency-driven atherosclerosis susceptibility in mice despite the induction of proatherogenic metabolic complications in the double knockout mice. | 31941380 |
| 2020-04-18 11:25:00 | The selected compounds were further confirmed to target PLTP both biochemically and biophysically and were shown to inhibit apoB secretion from hepatic cells with no apparent toxicity. | 31017809 |
| 2020-03-07 10:32:00 | PLTP-/- mice were protected from high-fat-diet-induced obesity and insulin resistance, compared with wild type mice. | 31220615 |
| 2019-11-02 13:01:00 | Profurin can interact with intracellular PLTP and promote its ubiquitination and proteasomal degradation, resulting in less PLTP secretion from the hepatocytes. Furin does not cleave PLTP; instead, it forms a complex with PLTP, likely through its prodomain | 29680823 |
| 2019-11-02 10:58:00 | these data show that PLTP plays a role in modulating the adaptive immune response toward a pro-inflammatory phenotype, which may be an additional contributor to its pro-atherogenic effects | 29735978 |
| Type | IDs |
|---|---|
| Synonymous | Bpife, OD107 |
| Gene |
UniProtKB-ID:
PLTP_MOUSE,
Q3UE59_MOUSE,
Q3UFS5_MOUSE
UniprotKB:
P55065,
Q3UE59,
Q3UFS5
UniParc:
UPI0000021553,
UPI00005AC8F4
EMBL:
AK149730,
AK148330,
U28960,
BC003782,
U37226
Ensembl:
ENSMUSG00000017754
KO:
mmu:18830
|
| Nucleutide sequences |
EMBL-CDS:
AAA87943.1,
AAH03782.1,
AAA80542.1,
BAE29052.1,
BAE28485.1
Ensembl_TRS:
ENSMUST00000109316,
ENSMUST00000059954
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000104939,
ENSMUSP00000061519
RefSeq:
XP_036015508.1,
NP_035255.1
|
| Others |
UniRef100:
UniRef100_P55065
UniRef90:
UniRef90_P55065
UniRef50:
UniRef50_P55065
UniGene:
Mm.6105
CCDS:
CCDS17063.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员