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18826 Lcp1

18826

Lcp1

lymphocyte cytosolic protein 1

protein-coding

Mus musculus

基因描述

Type Description
Definition lymphocyte cytosolic protein 1

研究结论

Date Results Publications
2021-03-27 14:42:00 Neutrophil L-Plastin Controls Ocular Paucibacteriality and Susceptibility to Keratitis. 32318063
2021-02-27 13:44:00 A novel regulatory role of TRAPPC9 in L-plastin-mediated osteoclast actin ring formation. 31453638
2020-01-11 10:39:00 Among the proteins found to preferentially bind clasped rather than the isolated alphaM and beta2 subunits was L-plastin (LCP1, also known as plastin-2), which binds to and maintains the inactive state of alphaMbeta2 integrin in vivo and thereby regulates leukocyte adhesion to integrin ligands under flow. 30333137
2019-11-30 10:10:00 Our data suggest that targeted disruption of L-plastin increases trabecular bone volume, and phosphorylation of Ser5 in L-plastin in the Lrrk1 signaling pathway may in part contribute to actin assembly in mature osteoclasts. 30136304
2019-09-21 10:42:00 It is shown that TNF-alpha signaling regulates the phosphorylation of serine-5 and -7 in L-plastin which increases the actin bundling capacity of L-plastin and hence the formation of nascent sealing zones in mouse osteoclasts. 30244178

名称对应

Type IDs
Synonymous AW536232, D14Ertd310e, LCP-1, Pls2, pp65
Gene
UniProtKB-ID: PLSL_MOUSE
UniprotKB: Q61233
UniParc: UPI0000021DA4
EMBL: D37837, AK030806, AK152891, AK088202, AK009211, AK153082, AK153206, AK030987, AK169728, AK149790, AK169833, BC022943, AK030996, AK151155
Ensembl: ENSMUSG00000021998
KO: mmu:18826
Nucleutide sequences
EMBL-CDS: BAE30161.1, BAE41332.1, BAE20456.1, BAC27208.1, BAB26141.1, BAE31574.1, BAC27205.1, BAE31707.1, BAE41398.1, BAE29087.1, BAC40207.1, BAE31806.1, AAH22943.1, BAA07085.1
Ensembl_TRS: ENSMUST00000124499, ENSMUST00000145303, ENSMUST00000131802
Protein sequencees
Ensembl_PRO: ENSMUSP00000117137, ENSMUSP00000116271, ENSMUSP00000121201
RefSeq: XP_036014400.1, XP_006518764.1, XP_006518766.1, NP_001234913.1, XP_006518762.1, XP_006518767.1, NP_032905.2
Others
UniRef100: UniRef100_Q61233
UniRef90: UniRef90_Q61233
UniRef50: UniRef50_Q61233
UniGene: Mm.153911, Mm.484415
CCDS: CCDS27276.1

全选

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