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18816 Serpinf2

18816

Serpinf2

serine (or cysteine) peptidase inhibitor, clade F, member 2

protein-coding

Mus musculus

基因描述

Type Description
Definition serine (or cysteine) peptidase inhibitor, clade F, member 2

研究结论

Date Results Publications
2020-02-01 10:42:00 Suppression of fibrinolysis by alpha2AP appears essential for stasis-induced thrombus development, which suggests that targeting alpha2AP may prove useful for preventing venous thrombosis. 31395599
2018-04-21 10:10:00 These results suggest that alpha2AP negatively affects osteoblast differentiation and function by inhibiting the Wnt/beta-catenin pathway. 28677806
2016-08-20 10:18:00 alpha2AP has a profibrotic effect probably not by the action as a plasmin inhibitor, and the blocking of alpha2AP exerts an antifibrotic effect in humans and mice with systemic sclerosis 26743600
2016-02-20 10:23:00 A2AP is not significantly affected by the Pla protease during pneumonic plague, and although A2AP participates in immune modulation in the lungs, it has limited impact on the course or ultimate outcome of the infection. 26438794
2015-04-25 10:25:00 a2AP deficiency enhanced thrombus dissolution, increased cerebral blood flow, reduced brain infarction, and decreased brain swelling. 25256235

名称对应

Type IDs
Synonymous AI747498, Pli, Serpimf2
Gene
UniProtKB-ID: A2AP_MOUSE, Q5ND36_MOUSE
UniprotKB: Q61247, Q5ND36
UniParc: UPI0000001A27
EMBL: BC026756, GQ896354, GQ896353, Z36774
Ensembl: ENSMUSG00000038224
KO: mmu:18816
Nucleutide sequences
EMBL-CDS: AAH26756.1, CAA85350.1, ACX48447.1, ACX48446.1
Ensembl_TRS: ENSMUST00000108437, ENSMUST00000043696
Protein sequencees
Ensembl_PRO: ENSMUSP00000048704, ENSMUSP00000104076
RefSeq: NP_032904.1
Others
UniRef100: UniRef100_Q61247
UniRef90: UniRef90_Q61247
UniRef50: UniRef50_Q61247
UniGene: Mm.279733
CCDS: CCDS25046.1

全选

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研究热度

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