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1880 GPR183

1880

GPR183

G protein-coupled receptor 183

protein-coding

Homo sapiens

基因描述

Type Description
Definition G protein-coupled receptor 183

研究结论

Date Results Publications
2020-10-24 14:02:00 Orphan G-protein coupled receptor 183 (GPR183) potentiates insulin secretion and prevents glucotoxicity-induced beta-cell dysfunction. 31550518
2019-08-31 11:46:00 these data implicate the EBI2-oxysterol axis in inflammatory bowel disease pathogenesis 30742043
2017-11-25 13:10:00 These data suggest a significant role for EBI2 in human CD4(+) T cell migration, notably in patients with multiple sclerosis. 28052250
2017-09-02 12:59:00 Studies provide evidence that EBI2 and oxysterols are important players not only in the immune system but also in the central nervous system. Proper functioning of the EBI2/oxysterol system seems crucial for healthy physiology and prevention of the onset or progression of several neurodegenerative diseases. [review] 26898310
2017-08-19 10:52:00 Human EBI2 (GPR183) expression in mice leads to an abnormally expanded CD5+ B1a B-cell subset and chronic lymphocytic leukemia-like B-cell malignancies. 28003273

名称对应

Type IDs
Synonymous EBI2, hEBI2
Gene
UniProtKB-ID: GP183_HUMAN, A0A024RDX2_HUMAN
UniprotKB: P32249, A0A024RDX2
UniParc: UPI0000001068
EMBL: AK313443, BC020752, AK292091, AK223390, AL160155, CH471085, L08177
Ensembl: ENSG00000169508
KO: hsa:1880
Nucleutide sequences
EMBL-CDS: BAG36232.1, BAD97110.1, EAX09018.1, BAF84780.1, AAA35924.1, AAH20752.1, EAX09019.1
Gene_ORFName: hCG_29510
Ensembl_TRS: ENST00000376414
Protein sequencees
Ensembl_PRO: ENSP00000365596
RefSeq: XP_016875894.1, NP_004942.1
Others
UniRef100: UniRef100_P32249
UniRef90: UniRef90_P32249
UniRef50: UniRef50_P32249
UniGene: Hs.784
CCDS: CCDS9492.1

全选

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研究热度

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