| Type | Description |
|---|---|
| Definition | phospholipase C, beta 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:24:00 | Expression and localization of endogenous phospholipase Cbeta3 confined to basal cells in situ of immature ducts and adult excretory ducts of submandibular gland of mice. | 31898936 |
| 2017-08-26 13:11:00 | Data, including data from studies using transgenic/knockout mice, suggest that Ppp1ca and Gnb1 interact in quiescent platelets; then, Ppp1ca and Plcb3 interact during platelet aggregation; thus, Gnb1 enlists Ppp1ca to modulate G protein-coupled receptor signaling. (Ppp1ca = protein phosphatase 1, catalytic subunit alpha; Gnb1 = guanine nucleotide-binding protein, subunit beta-1; Plcb3 = phospholipase C, subunit beta-3) | 28615442 |
| 2016-06-11 10:57:00 | Gnb isoforms control a signaling pathway comprising Rac1, Plcbeta2, and Plcbeta3 leading to LFA-1 activation and neutrophil arrest in vivo | 26468229 |
| 2014-09-27 12:49:00 | Plcb3-deficient mice spontaneously develop atopic dermatitis-like skin lesions. | 24412367 |
| 2012-12-08 11:21:00 | Data suggest that PLCbeta3 acts as a negative regulator of VEGF- (vascular endothelial growth factor A-) mediated vascular hyperpermeability through intracellular calcium signaling. | 22674805 |
| Type | IDs |
|---|---|
| Synonymous | mKIAA4098 |
| Gene |
UniProtKB-ID:
PLCB3_MOUSE,
Q8CI86_MOUSE
UniprotKB:
P51432,
Q8CI86
UniParc:
UPI00000E8CA8,
UPI0000565C81
EMBL:
BC035928,
U43144,
AK146793,
CH466612
Ensembl:
ENSMUSG00000024960
KO:
mmu:18797
|
| Nucleutide sequences |
EMBL-CDS:
BAE27436.1,
AAA85199.1,
EDL33267.1,
AAH35928.1
Ensembl_TRS:
ENSMUST00000025912
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000025912
RefSeq:
NP_001277278.1,
NP_032900.2,
XP_006526830.1,
XP_006526829.1
|
| Others |
UniRef100:
UniRef100_Q8CI86,
UniRef100_P51432
UniRef90:
UniRef90_P51432,
UniRef90_A0A4U1FM70
UniRef50:
UniRef50_Q01970,
UniRef50_Q99JE6
UniGene:
Mm.273204
CCDS:
CCDS70925.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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