| Type | Description |
|---|---|
| Definition | phospholipase C, beta 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-04-13 12:32:00 | Results show that phospholipase C beta 2 (PLCbeta2) inhibits the virus-induced expression of pro-inflammatory cytokines by interacting with and inhibiting transforming growth factor-beta-activated kinase 1 (TAK1) activation. | 30765691 |
| 2017-11-11 11:59:00 | Data suggest the a decrease in migration of hematopoietic stem progenitor cells (HSPCs) can be explained by impaired calcium release in phospholipase C-beta2 (PLC-beta2) knockout (KO) mice and a high baseline level of heme oxygenase 1 (HO-1), an enzyme that negatively regulates cell migration. | 27704316 |
| 2017-05-06 16:31:00 | tristetraprolin is not involved in LPS-mediated destabilization of PLCbeta-2 mRNA in macrophages | 28124257 |
| 2016-06-11 10:57:00 | Gnb isoforms control a signaling pathway comprising Rac1, Plcbeta2, and Plcbeta3 leading to LFA-1 activation and neutrophil arrest in vivo | 26468229 |
| 2013-06-22 11:01:00 | Galphaq-coupled Lpar1 regulates cell proliferation and migration by activating two distinct PLC-beta isozymes, PLC-beta1 and PLC-beta2, respectively. | 23478264 |
| Type | IDs |
|---|---|
| Synonymous | AI550384, B230205M18Rik, B230399N12 |
| Gene |
UniProtKB-ID:
PLCB2_MOUSE,
E9PYI3_MOUSE,
Q3V3V2_MOUSE
UniprotKB:
A3KGF7,
E9PYI3,
Q3V3V2
UniParc:
UPI00005AB5CA,
UPI00000EB850,
UPI00005B2575,
UPI0000683F0C,
UPI0001DD353E,
UPI00001EF730
EMBL:
AL772255,
AK045469,
AK169442,
AY902324,
AK031502
Ensembl:
ENSMUSG00000040061
KO:
mmu:18796
|
| Nucleutide sequences |
EMBL-CDS:
AAX90609.1,
BAC32384.1,
BAE41180.1,
BAE20476.1
Ensembl_TRS:
ENSMUST00000102524,
ENSMUST00000159756
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099583,
ENSMUSP00000124364
RefSeq:
NP_808236.2,
XP_036015459.1,
XP_006498998.1,
NP_001277719.1,
XP_017171846.1,
XP_017171848.1
|
| Others |
UniRef100:
UniRef100_Q3V3V2,
UniRef100_A3KGF7,
UniRef100_E9PYI3
UniRef90:
UniRef90_A3KGF7,
UniRef90_Q3V3V2
UniRef50:
UniRef50_Q00722,
UniRef50_Q3V3V2
UniGene:
Mm.215156
CCDS:
CCDS16582.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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