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18791 Plat

18791

Plat

plasminogen activator, tissue

protein-coding

Mus musculus

基因描述

Type Description
Definition plasminogen activator, tissue

研究结论

Date Results Publications
2021-02-06 13:59:00 tPA Deficiency Underlies Neurovascular Coupling Dysfunction by Amyloid-beta. 32928888
2021-02-06 13:58:00 Interacting hepatic PAI-1/tPA gene regulatory pathways influence impaired fibrinolysis severity in obesity. 32657780
2020-05-30 12:57:00 This effect requires endothelial NMDAR and is t-PA-dependent. These neurodevelopmental data reinforce the debate regarding safety of molecules with NMDA-antagonist properties administered to preterm and term neonates. 31392351
2018-08-18 11:49:00 Sata suggest that tissue-type plasminogen activator (tPA) regulates nocturnal wheel-running activity, and that tPA differentially affects suprachiasmatic nucleus-driven nocturnal activity rhythms and activity driven by fasting or temporal food restriction. 29370799
2018-03-03 10:51:00 Our findings suggest that isoflurane pretreatment could attenuate tPA-exaggerated brain ischemic injury, by reducing tPA-induced LRP/NF-kappaB/Cox-2 in endothelial cells, endothelial MMP-2 and MMP-9 activation, and subsequent pro-apoptotic molecule in neurons after oxygen/glucose deprivation and reperfusion. 28539818

名称对应

Type IDs
Synonymous AU020998, AW212668, D8Ertd2e, tPA
Gene
UniProtKB-ID: TPA_MOUSE
UniprotKB: P11214
UniParc: UPI0000193258
EMBL: BC011256, AK135857, AK135965, J03520, BC061508, BC057967
Ensembl: ENSMUSG00000031538
KO: mmu:18791
Nucleutide sequences
EMBL-CDS: BAE22698.1, BAE22749.1, AAH61508.1, AAA40470.1, AAH57967.1, AAH11256.1
Ensembl_TRS: ENSMUST00000033941
Protein sequencees
Ensembl_PRO: ENSMUSP00000033941
RefSeq: XP_036009719.1, XP_036009720.1, NP_032898.2
Others
UniRef100: UniRef100_P11214
UniRef90: UniRef90_P19637
UniRef50: UniRef50_P00750
UniGene: Mm.154660
CCDS: CCDS22183.1

全选

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