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18783 Pla2g4a

18783

Pla2g4a

phospholipase A2, group IVA (cytosolic, calcium-dependent)

protein-coding

Mus musculus

基因描述

Type Description
Definition phospholipase A2, group IVA (cytosolic, calcium-dependent)

研究结论

Date Results Publications
2020-11-28 13:10:00 PLA2G4A/cPLA2-mediated lysosomal membrane damage leads to inhibition of autophagy and neurodegeneration after brain trauma. 31238788
2020-07-11 10:07:00 The data implicate lysosomal defects in pathophysiology of spinal cord injury and for the first time indicate that cPLA2 activation leads to lysosomal damage causing neuronal autophagosome accumulation associated with neuronal cell death. 31296844
2020-02-22 10:56:00 distinct contribution of cPLA2alpha and sPLA2-IIA to the eicosanoid profile in arthritis 31129176
2019-12-14 10:39:00 cPLA2 is a novel target of tumor suppressor gene, Mig-6, in the uterus. 30773264
2019-08-24 11:23:00 These results suggest a role of cPLA2 activation in facilitating oligomeric Abeta endocytosis by microglial cells through regulation of the membrane-cytoskeleton connectivity. 30112630

名称对应

Type IDs
Synonymous Pla2g4, cPLA2, cPLA2-alpha, cPLA2alpha
Gene
UniProtKB-ID: PA24A_MOUSE, Q3UMQ1_MOUSE, Q9DBX5_MOUSE
UniprotKB: P47713, Q3UMQ1, Q9DBX5
UniParc: UPI00000E5FE9, UPI00000274AC
EMBL: M72394, AK144750, AK004701, AC120138, BC003816, AC158151
Ensembl: ENSMUSG00000056220
KO: mmu:18783
Nucleutide sequences
EMBL-CDS: AAB00796.1, AAH03816.1, BAE26047.1, BAB23486.1
Ensembl_TRS: ENSMUST00000070200, ENSMUST00000111926
Protein sequencees
Ensembl_PRO: ENSMUSP00000070868, ENSMUSP00000107557
RefSeq: NP_001292561.1, NP_032895.1
Others
UniRef100: UniRef100_Q9DBX5, UniRef100_P47713
UniRef90: UniRef90_P47712
UniRef50: UniRef50_P47712
UniGene: Mm.4186
CCDS: CCDS15352.1

全选

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研究热度

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