| Type | Description |
|---|---|
| Definition | polycystic kidney disease 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:26:00 | Intravascular flow stimulates PKD2 (polycystin-2) channels in endothelial cells to reduce blood pressure. | 32364494 |
| 2020-12-12 13:29:00 | Deletion of cardiac polycystin 2/PC2 results in increased SR calcium release and blunted adrenergic reserve. | 32946258 |
| 2020-11-21 13:30:00 | Polycystin 2 is increased in disease to protect against stress-induced cell death. | 31941974 |
| 2020-11-21 13:20:00 | TRPP2 associates with STIM1 to regulate cerebral vasoconstriction and enhance high salt intake-induced hypertensive cerebrovascular spasm. | 31541223 |
| 2020-07-04 12:18:00 | Data show that mice with kidney-specific polycystin 2 (PC2) knockout, knockdown of mitofusin 2 (MFN2) rescued defective mitochondrial Ca(2+) transfer. | 31064883 |
| Type | IDs |
|---|---|
| Synonymous | C030034P18Rik, PC2, TRPP2 |
| Gene |
UniProtKB-ID:
PKD2_MOUSE
UniprotKB:
O35245
UniParc:
UPI0002507A9E,
UPI0002507AA0,
UPI0002507A9F,
UPI0001F790E7,
UPI00001A3D1D
EMBL:
Y14120,
Y14112,
Y14117,
AF242389,
Y14119,
Y13278,
Y14114,
AC124106,
AC123687,
Y14109,
Y14107,
AK053502,
FJ609779,
Y14110,
Y14105,
AF014010,
Y14111,
Y14108,
Y14106,
Y14118,
Y14115,
Y14116,
Y14113
Ensembl:
ENSMUSG00000034462
KO:
mmu:18764
|
| Nucleutide sequences |
EMBL-CDS:
BAC35407.1,
AAG13267.1,
ACN11624.1,
CAA74552.1,
AAC53388.1,
CAA74551.1,
CAA73727.1
Ensembl_TRS:
ENSMUST00000086831
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000084041
RefSeq:
XP_006534878.1,
NP_032887.3
|
| Others |
UniRef100:
UniRef100_O35245
UniRef90:
UniRef90_O35245
UniRef50:
UniRef50_O35245
UniGene:
Mm.6442,
Mm.483692
CCDS:
CCDS19487.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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