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187639 wve-1

187639

wve-1

WAVE (actin cytoskeleton modulator) homolog

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition WAVE (actin cytoskeleton modulator) homolog

研究结论

Date Results Publications
2018-03-31 12:02:00 EM studies in adults depleted of branched actin regulators support that WVE-1 maintains established junctions, presumably through its trafficking effect on Cadherin. 29223862
2015-08-22 10:06:00 The WAVE complex is the main activator of the Arp2/3 complex for actin filament nucleation and assembly in the lamellipodia of moving cells. 25355952
2013-06-29 11:28:00 WAVE/SCAR promotes endocytosis and early endosome morphology in polarized C. elegans epithelia. 23510716
2012-12-22 10:44:00 UNC-40/DCC, SAX-3/Robo, and VAB-1/Eph polarize F-actin during embryonic morphogenesis by regulating the WAVE/SCAR actin nucleation complex. 22876199
2011-12-03 10:26:00 results support a model in which the MIG-15 kinase and the UNC-116-WVE-1 complex act on opposite sides of the growth cone to promote robust directional migration 21937599

名称对应

Type IDs
Gene
UniProtKB-ID: F5GUF0_CAEEL, Q9XVK6_CAEEL
UniprotKB: F5GUF0, Q9XVK6
UniParc: UPI000209E18E, UPI000021CE9C
EMBL: BX284601
EnsemblGenome: WBGene00006958
KO: cel:CELE_R06C1.3
Nucleutide sequences
EMBL-CDS: CCA65600.1, CAB03220.2
Gene_ORFName: CELE_R06C1.3, R06C1.3, R06C1.3, CELE_R06C1.3
Protein sequencees
RefSeq: NP_001251762.1, NP_001370005.1
Others
UniRef100: UniRef100_Q9XVK6
UniRef90: UniRef90_Q9XVK6
UniRef50: UniRef50_Q9XVK6
UniGene: Cel.159

全选

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研究热度

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