| Type | Description |
|---|---|
| Definition | protein kinase D1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-27 14:45:00 | Inhibition of protein kinase D by CID755673 promotes maintenance of the pluripotency of embryonic stem cells. | 32747433 |
| 2020-09-05 13:55:00 | A role for PKD1 in insulin secretion downstream of P2Y1 receptor activation in mouse and human islets. | 31591827 |
| 2020-06-20 12:56:00 | Prkd1 knockdown was enough to block dissemination of murine mammary tumor organoids. Prkd1 knockdown in vivo blocked primary tumor invasion and distant metastasis in a mouse model of basal breast cancer. Findings suggest a novel molecular framework whereby Twist1 directly drives the transcriptional upregulation of Prkd1, whose activity promotes ECM-directed invasion, and metastasis without loss of epithelial identity. | 31676574 |
| 2020-05-30 12:59:00 | mu is one key factor for oocyte maturation through its roles on the spindle organization and actin filament distribution. | 30912144 |
| 2019-10-05 10:58:00 | deletion of PKD1 promotes expression of the beta3-adrenergic receptor (ADRB3) in a CCAAT/enhancer binding protein (C/EBP)-alpha- and delta-dependent manner, which leads to the elevated expression of beige markers in adipocytes and subcutaneous adipose tissue. | 30389661 |
| Type | IDs |
|---|---|
| Synonymous | PKD, PKD1, Pkcm, Prkcm |
| Gene |
UniProtKB-ID:
KPCD1_MOUSE
UniprotKB:
Q62101
UniParc:
UPI0000214D7C
EMBL:
CT010578,
Z34524,
AC099603,
CT009740,
AC154543
Ensembl:
ENSMUSG00000002688
KO:
mmu:18760
|
| Nucleutide sequences |
EMBL-CDS:
CAA84283.1
Ensembl_TRS:
ENSMUST00000002765
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000002765
RefSeq:
NP_001369745.1,
XP_006515653.1,
NP_032884.2,
XP_006515654.1,
NP_001369744.1,
NP_001369743.1,
XP_006515649.1,
XP_036013143.1
|
| Others |
UniRef100:
UniRef100_Q62101
UniRef90:
UniRef90_Q62101
UniRef50:
UniRef50_Q62101
UniGene:
Mm.133719
CCDS:
CCDS49059.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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