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18741 Pitx2

18741

Pitx2

paired-like homeodomain transcription factor 2

protein-coding

Mus musculus

基因描述

Type Description
Definition paired-like homeodomain transcription factor 2

研究结论

Date Results Publications
2020-06-27 10:09:00 single cell transcriptome analysis of Pitx2 during murine heart development 31201182
2020-05-09 10:23:00 Allele-specific chromatin immunoprecipitation sequencing on hybrid heterozygous enhancer knockout mice revealed that long-range interaction of an AF-associated region with the Pitx2c promoter was required for maintenance of the Pitx2c promoter chromatin state 31636200
2019-04-27 11:02:00 the c-isoform of PITX2 transcription factor modifies the myogenic potential of dystrophic-deficient satellite cells. 29641992
2019-03-09 11:55:00 Studies demonstrate that the homeodomain transcription factor Pitx2 has a postmitotic role in maintaining skeletal muscle integrity and energy homeostasis in fetal muscle fibers. 30414844
2019-01-26 12:22:00 Using Pitx2/3 single and double mutant mice that provide genetic models of deregulated redox states, we demonstrate that moderate overproduction of results in premature differentiation of satellite cells while high levels lead to their senescence and regenerative failure 30106373

名称对应

Type IDs
Synonymous 9430085M16Rik, Brx1, Brx1b, Munc30, Otlx2, Ptx2, Rieg
Gene
UniProtKB-ID: PITX2_MOUSE, B1VD84_MOUSE, Q6DIA6_MOUSE, B1VD85_MOUSE
UniprotKB: P97474, B1VD84, Q6DIA6, B1VD85
UniParc: UPI000002B124, UPI0000022D86, UPI00016428DE, UPI00016428DF, UPI0000025620
EMBL: AM940439, U70132, U80036, U80010, AB006320, AJ243597, BC075660, AM940438, AF048724, AF048723, AF201091, AB006321, U80011
Ensembl: ENSMUSG00000028023
KO: mmu:18741
Nucleutide sequences
EMBL-CDS: AAC40086.1, AAF44618.1, AAB38864.1, AAC40087.1, BAA75247.1, AAC53119.1, AAB38505.1, CAB65259.1, AAC53120.1, BAA75248.1, CAP79627.1, AAH75660.1, CAP91067.1
Ensembl_TRS: ENSMUST00000172645, ENSMUST00000106382, ENSMUST00000042587, ENSMUST00000174661
Protein sequencees
Ensembl_PRO: ENSMUSP00000134692, ENSMUSP00000047359, ENSMUSP00000133756, ENSMUSP00000101990
RefSeq: XP_006501196.1, NP_001273871.1, NP_001035969.1, XP_006501194.1, NP_035228.2, NP_001035967.1, NP_001273977.1, XP_006501195.1
Others
UniRef100: UniRef100_P97474, UniRef100_B1VD84, UniRef100_Q6DIA6
UniRef90: UniRef90_Q9R0W1, UniRef90_P97474
UniRef50: UniRef50_P97474, UniRef50_P97474-3
UniGene: Mm.246804
CCDS: CCDS38630.1, CCDS38631.1, CCDS71316.1, CCDS17830.1

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