| Type | Description |
|---|---|
| Definition | paired-like homeodomain transcription factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:26:00 | Variation in mouse pelvic morphology maps to locations enriched in Sox9 Class II and Pitx1 regulatory features. | 32017444 |
| 2020-10-03 12:50:00 | Bone-Specific Overexpression of PITX1 Induces Senile Osteoporosis in Mice Through Deficient Self-Renewal of Mesenchymal Progenitors and Wnt Pathway Inhibition. | 30837642 |
| 2020-04-25 12:26:00 | The PITX1 is specifically expressed in TPCs, where it co-localizes with SOX2 and TRP63 and determines cell fate in mouse and human squamous cell carcinoma (SCC). | 30713093 |
| 2019-04-27 10:16:00 | Pitx1 is controlled by an enhancer (Pen) that shows activity in forelimbs and hindlimbs. Forelimbs and hindlimbs have fundamentally different chromatin configurations, whereby Pen and Pitx1 interact in hindlimbs and are physically separated in forelimbs. Structural variants can convert the inactive into the active conformation, thereby inducing Pitx1 misexpression in forelimbs. | 30262816 |
| 2018-05-26 11:42:00 | Pitx1 distal enhancer loss have only mild effects on Pitx1 expression in the hindlimb and no overt effects on hindlimb or mandibular morphology. | 29549111 |
| Type | IDs |
|---|---|
| Synonymous | Bft, P-OTX, Potx, Ptx1 |
| Gene |
UniProtKB-ID:
PITX1_MOUSE,
Q3UQH0_MOUSE
UniprotKB:
P70314,
Q3UQH0
UniParc:
UPI0000001921
EMBL:
U54499,
U71206,
AK142455,
BC012696,
U70371
Ensembl:
ENSMUSG00000021506
KO:
mmu:18740
|
| Nucleutide sequences |
EMBL-CDS:
AAC52716.1,
AAH12696.1,
AAC53059.1,
AAB16860.1,
BAE25071.1
Ensembl_TRS:
ENSMUST00000021968
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000021968
RefSeq:
NP_035227.1,
XP_006517220.1,
XP_006517221.1
|
| Others |
UniRef100:
UniRef100_P70314
UniRef90:
UniRef90_P70314
UniRef50:
UniRef50_P70314
UniGene:
Mm.135195
CCDS:
CCDS26556.1
|
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|---|---|---|---|---|---|---|---|---|
| Refseq |
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