| Type | Description |
|---|---|
| Definition | E2F transcription factor 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-02 13:24:00 | Long non-coding RNA LINC00337 induces autophagy and chemoresistance to cisplatin in esophageal squamous cell carcinoma cells via upregulation of TPX2 by recruiting E2F4. | 32239565 |
| 2019-10-05 10:25:00 | overexpressing p130 or E2F4 significantly improved migration but not proliferation of mMSCs. Our data suggest that cell cycle regulation may be involved in p130/E2F4-mediated changes in the multipotential abilities of bone-marrow-derived mesenchymal stem cells (MSCs). | 29987913 |
| 2019-07-20 11:39:00 | A point mutation in LxCxE motif of KDM5A/RBP2 renders it incapable of 130 kDa retinoblastoma-associated protein (p130)-interaction and hence, repression of E2F transcription factor 4 and (E2F)-regulated gene promoters. | 29059406 |
| 2019-05-25 11:11:00 | E2F4 transcriptional repressor physically associates to the VHL demethylated promoter. These observations together with the finding of elevated E2F4 levels in early-onset preeclampsia (E-PE) placentae suggest that E2F4 inactivates VHL gene expression in E-PE due to enhanced binding to the VHL promoter as a consequence of the reduced methylation status of its binding site. | 30053437 |
| 2019-03-09 12:30:00 | HSP27 promotes cell cycle progression of MRC-5 cells by suppressing expression of the transcriptional repressors E2F-4 and p130 | 30166342 |
| Type | IDs |
|---|---|
| Synonymous | E2F-4 |
| Gene |
UniProtKB-ID:
E2F4_HUMAN
UniprotKB:
Q16254
UniParc:
UPI000002EFCB
EMBL:
AF250378,
U15641,
AB451292,
AB451425,
AF527540,
CH471092,
X86096,
BC033180,
S75174,
AC040160
Ensembl:
ENSG00000205250
KO:
hsa:1874
|
| Nucleutide sequences |
EMBL-CDS:
AAF65226.1,
AAC50119.1,
BAG70106.1,
EAW83094.1,
BAG70239.1,
CAA60050.2,
AAM77918.1,
AAH33180.1,
AAB32597.1
Ensembl_TRS:
ENST00000379378
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000368686
RefSeq:
NP_001941.2
|
| Others |
UniRef100:
UniRef100_Q16254
UniRef90:
UniRef90_Q16254
UniRef50:
UniRef50_Q16254
UniGene:
Hs.108371
CCDS:
CCDS32464.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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