| Type | Description |
|---|---|
| Definition | phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha |
| Date | Results | Publications |
|---|---|---|
| 2018-12-29 12:04:00 | PIP5K1alpha was found to be required for AKT activation and calcium release, both of which were important for skeletal muscle differentiation. | 29426367 |
| 2018-05-19 10:30:00 | these results support that PIP5Kalpha can positively mediate TLR2-associated immune responses through Phosphatidylinositol 4,5-bisphosphate production in microglial cells. | 28711717 |
| 2014-09-27 12:01:00 | Data suggest that c-Fos (proto-oncogene protein c-fos; not c-Jun) regulates phospholipid synthesis in cell nucleus; c-Fos localizes to nucleus and modulates genetic transcription through activation of Pip5k1. | 24819416 |
| 2013-04-27 11:19:00 | optimal PIP5KIgamma and PI(4,5)P(2) expression, by osteoclasts, are essential for skeletal homeostasis | 23300084 |
| 2012-11-24 11:22:00 | Our findings suggest that PI4P5Kalpha plays a complex role in restricting insulin release from pancreatic beta-cells through helping to maintain plasma membrane PIP(2) levels and integrity of the actin cytoskeleton under both basal and stimulatory conditions. | 21270258 |
| Type | IDs |
|---|---|
| Synonymous | PI4P5K-I[a], PIP5K1-alpha, PIP5KIalpha, Pipk5a |
| Gene |
UniProtKB-ID:
PI51A_MOUSE
UniprotKB:
P70182
UniParc:
UPI0000D8B390,
UPI0003B2838F,
UPI0000020EDA
EMBL:
D86177,
BC003763,
AK151984,
AC131769,
AC087062,
AK158062,
AK150898,
BC031774
Ensembl:
ENSMUSG00000028126
KO:
mmu:18720
|
| Nucleutide sequences |
EMBL-CDS:
BAE30850.1,
BAA13031.1,
BAE29943.1,
BAE34344.1,
AAH03763.1,
AAH31774.1
Ensembl_TRS:
ENSMUST00000107236,
ENSMUST00000107233
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000102855,
ENSMUSP00000102852
RefSeq:
NP_032873.2,
XP_036018829.1,
XP_036018831.1,
XP_036018832.1,
XP_036018830.1,
NP_001280636.1
|
| Others |
UniRef100:
UniRef100_P70182
UniRef90:
UniRef90_Q99755
UniRef50:
UniRef50_Q99755
UniGene:
Mm.296409
CCDS:
CCDS38542.1,
CCDS79980.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员