| Type | Description |
|---|---|
| Definition | prolactin induced protein |
| Date | Results | Publications |
|---|---|---|
| 2020-04-25 12:24:00 | we observed that the deficiency of Pip led to anomalies in the histology of lymphoid organs including the lymph nodes, spleen and thymus. We also observed anomalies in the morphology of the Eustachian tube and tympanic membrane in Pip deficient mice. Collectively, these data strongly suggest that Pip is an important regulator of immune responses. | 31447246 |
| 2019-02-02 11:25:00 | studies show that deficiency of PIP significantly affects intracellular signaling events leading to decreased pro-inflammatory cytokine production, and further confirms a role for PIP as an important immunoregulatory protein. This direct link between PIP and cell-mediated immunity, a key component of the immune system that is critical for cancer control, may have significant therapeutic implications. | 29536339 |
| 2016-12-31 10:45:00 | Recent work with Pip-deficient mice, linking PIP not only to a role in innate immunity but for the first time, providing evidence for a role in cell-mediated immunity. [Review] | 27602994 |
| 2015-06-20 12:22:00 | The findings implicate PIP as an important regulator of CD4(+) Th1-cell-mediated immunity. | 25594453 |
| 2010-03-08 12:04:00 | these studies lend support to an immunomodulatory role for PIP in vivo and provide further insights into potentially novel signaling pathways and regulatory networks for PIP | 20052012 |
| Type | IDs |
|---|---|
| Synonymous | GCDFP-15, GP17, SMGP |
| Gene |
UniProtKB-ID:
PIP_MOUSE,
Q3UU48_MOUSE
UniprotKB:
P02816,
Q3UU48
UniParc:
UPI0000020E6E
EMBL:
BC028889,
X02510,
S73282,
AB017918,
AB017907,
AK138795
Ensembl:
ENSMUSG00000058499
KO:
mmu:18716
|
| Nucleutide sequences |
EMBL-CDS:
AAH28889.1,
BAA75745.1,
BAA75747.1,
CAA26346.1,
AAB31990.2,
BAE23780.1
Ensembl_TRS:
ENSMUST00000075351
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000074818
RefSeq:
NP_032869.2
|
| Others |
UniRef100:
UniRef100_P02816
UniRef90:
UniRef90_P02816
UniRef50:
UniRef50_P02816
UniGene:
Mm.214755
CCDS:
CCDS39469.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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