| Type | Description |
|---|---|
| Definition | proviral integration site 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-28 19:08:00 | PIM2 deletion alleviates lipopolysaccharide (LPS)-induced respiratory distress syndrome (ARDS) by suppressing NLRP3 inflammasome. | 33333710 |
| 2020-11-21 13:19:00 | TRAF3 regulates the oncogenic proteins Pim2 and c-Myc to restrain survival in normal and malignant B cells. | 31501481 |
| 2019-09-21 10:50:00 | T cells deficient in PIM-2 demonstrated increased T cell differentiation toward Th1 subset, proliferation, and migration to target organs after allogeneic bone marrow transplantation, resulting in dramatically accelerated graft-versus-host disease (GVHD) severity. Restoration of PIM-2 expression markedly attenuated the pathogenicity of PIM-2-deficient T cells to induce GVHD. | 29781812 |
| 2019-05-25 10:04:00 | PIM2 might function as an important oncogene in gastric cancer | 30340823 |
| 2015-12-12 10:13:00 | studies define a pathway for limiting the regulation of Foxp3 function because the Pim-2 kinase represents a potential therapeutic target for modulating the Treg cell suppressive activities in controlling immune responses | 25987564 |
| Type | IDs |
|---|---|
| Synonymous | DXCch3, Pim-2 |
| Gene |
UniProtKB-ID:
PIM2_MOUSE,
Q8R1Z0_MOUSE
UniprotKB:
Q62070,
Q8R1Z0
UniParc:
UPI0000028629,
UPI00000E648D,
UPI00000278BE,
UPI00000278BF
EMBL:
L41495,
AL671978,
BC027376,
BC022727
KO:
mmu:18715
|
| Nucleutide sequences |
EMBL-CDS:
AAA98923.1,
AAA98922.1,
AAA98924.1,
AAH27376.1,
AAH22727.1
|
| Protein sequencees |
RefSeq:
NP_613072.1
|
| Others |
UniRef100:
UniRef100_Q62070,
UniRef100_Q62070-3
UniRef90:
UniRef90_Q62070
UniRef50:
UniRef50_Q62070
UniGene:
Mm.347478
CCDS:
CCDS29976.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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