| Type | Description |
|---|---|
| Definition | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:26:00 | Mutation-Associated Phenotypic Heterogeneity in Novel and Canonical PIK3CA Helical and Kinase Domain Mutants. | 32365913 |
| 2021-03-13 13:19:00 | Loss of Phosphatidylinositol 3-Kinase Activity in Regulatory T Cells Leads to Neuronal Inflammation. | 32414808 |
| 2020-08-22 15:28:00 | Blockade of VEGF-C signaling inhibits lymphatic malformations driven by oncogenic PIK3CA mutation. | 32513927 |
| 2020-05-30 11:42:00 | Study of experimentally induced anal cancer in transgenic mice demonstrates that activating mutations in Pik3ca drive anal carcinogenesis together with HPV16 oncogenes, and that the PI3K/mTOR pathway is a relevant target for therapeutic intervention. | 30530704 |
| 2020-04-11 10:28:00 | Inhibition of PI3Kalpha impairs skeletogenic responsiveness to BMPs and the acquired response to activin A of the Acvr1(R206H) allele. | 31373426 |
| Type | IDs |
|---|---|
| Synonymous | 6330412C24Rik, caPI3K, p110, p110alpha |
| Gene |
UniProtKB-ID:
PK3CA_MOUSE
UniprotKB:
P42337
UniParc:
UPI00001F06AE
EMBL:
CH466530,
U03279,
BC089038,
BC130228
Ensembl:
ENSMUSG00000027665
KO:
mmu:18706
|
| Nucleutide sequences |
EMBL-CDS:
AAH89038.1,
EDL34990.1,
AAA18334.1,
AAI30229.1
Ensembl_TRS:
ENSMUST00000108243,
ENSMUST00000029201
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000029201,
ENSMUSP00000103878
RefSeq:
NP_032865.2
|
| Others |
UniRef100:
UniRef100_P42337
UniRef90:
UniRef90_P42336
UniRef50:
UniRef50_P42336
UniGene:
Mm.260521
CCDS:
CCDS38409.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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