| Type | Description |
|---|---|
| Definition | polymeric immunoglobulin receptor |
| Date | Results | Publications |
|---|---|---|
| 2017-09-23 14:08:00 | RrgA, binds both polymeric immunoglobulin receptor (pIgR) and PECAM-1, whereas the choline binding protein PspC binds, but to a lower extent, only pIgR | 28515075 |
| 2016-08-27 11:44:00 | pIgR/SIgA deficiency in the airways leads to persistent activation of innate immune responses to resident lung microbiota, driving progressive small airway remodelling and emphysema. | 27046438 |
| 2016-04-02 10:55:00 | Increased autoimmune diabetes in Pigr-deficient NOD mice is due to a "Hitchhiking" interval that refines the genetic effect of Idd5.4. | 25835383 |
| 2015-08-29 10:41:00 | the polymeric immunoglobulin receptor (pIgR) is highly expressed by renal cyst-lining cells. pIgR expression is, in part, driven by aberrant pathway activation. | 25922073 |
| 2015-08-01 12:06:00 | In a mouse intestinal explant model, the heat-inactivated potential probiotic BB6378 increases intestinal pIgR expression in a site-specific manner on the epithelium via MyD88. | 21967771 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
PIGR_MOUSE
UniprotKB:
O70570
UniParc:
UPI0000001CB3
EMBL:
Y16532,
Y16526,
Y16529,
U06431,
U83434,
Y16524,
Y16528,
Y16530,
U83431,
Y16531,
U83432,
U83427,
Y16525,
U83430,
U83428,
U83429,
U83433,
Y16527
Ensembl:
ENSMUSG00000026417
KO:
mmu:18703
|
| Nucleutide sequences |
EMBL-CDS:
CAA76272.1,
AAA67440.1,
AAC53585.1
Ensembl_TRS:
ENSMUST00000027675
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000027675
RefSeq:
NP_035212.2
|
| Others |
UniRef100:
UniRef100_O70570
UniRef90:
UniRef90_O70570
UniRef50:
UniRef50_P01833
UniGene:
Mm.276414
CCDS:
CCDS15260.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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