| Type | Description |
|---|---|
| Definition | protein interacting with C kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-22 15:27:00 | PICK1 attenuates high glucose-induced pancreatic beta-cell death through the PI3K/Akt pathway and is negatively regulated by miR-139-5p. | 31735337 |
| 2019-12-14 12:15:00 | These data support a novel interaction and model where PICK1 mediates Arc regulation of AMPARs particularly under depolarizing conditions. | 30279480 |
| 2019-11-02 11:03:00 | These findings demonstrate that it is possible to identify potent, selective PICK1-GluA2 inhibitors which may prove useful for treatment of neurodegenerative disorders. | 30194389 |
| 2019-05-18 12:20:00 | PICK1 plays a pivotal role in sepsis-induced acute lung injury by regulating glutathione synthesis via affecting the substrate-specific subunit of lung cystine/glutamate transporter, xCT. | 29471107 |
| 2019-02-02 10:58:00 | The beta cell-specific deletion of Pick1 in mice led to hyperglycemia and eventually to diabetes. | 29298842 |
| Type | IDs |
|---|---|
| Synonymous | Prkcabp |
| Gene |
UniProtKB-ID:
E9PUZ5_MOUSE,
Q8C1W2_MOUSE
UniprotKB:
E9PUZ5,
Q8C1W2
UniParc:
UPI00000EA128,
UPI0000021589
EMBL:
AK090155,
AL591921
Ensembl:
ENSMUSG00000068206
KO:
mmu:18693
|
| Nucleutide sequences |
EMBL-CDS:
BAC41117.1
Ensembl_TRS:
ENSMUST00000163571,
ENSMUST00000018295,
ENSMUST00000166155
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000129468,
ENSMUSP00000018295,
ENSMUSP00000128126
RefSeq:
NP_032863.2,
NP_001039023.1
|
| Others |
UniRef100:
UniRef100_Q8C1W2,
UniRef100_E9PUZ5
UniRef90:
UniRef90_Q9EP80,
UniRef90_E9QAC6
UniRef50:
UniRef50_Q9NRD5,
UniRef50_Q9EP80
UniGene:
Mm.259464
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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