| Type | Description |
|---|---|
| Definition | ATP-binding cassette, sub-family B (MDR/TAP), member 1A |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 16:00:00 | Mdr1a, Bcrp and Mrp2 regulate the efficacy and toxicity of mesaconitine and hypaconitine by altering their tissue accumulation and in vivo residence. | 33171190 |
| 2020-11-21 13:19:00 | Sex-, feeding-, and circadian time-dependency of P-glycoprotein expression and activity - implications for mechanistic pharmacokinetics modeling. | 31324853 |
| 2020-08-22 15:26:00 | Age dependency of cerebral P-glycoprotein function in wild-type and APPPS1 mice measured with PET. | 30354871 |
| 2019-08-17 10:05:00 | WYE354 stimulated the ATPase activity of ABCB1, which was consistent with in silico predictions using a human ABCB1 mouse homology model, indicating that WYE354 is a potent substrate of ABCB1. | 30942458 |
| 2019-06-29 10:35:00 | The activation of P-Glycoprotein, Abcb1a, -mediated ATP hydrolysis by methadone was monophasic, whereas loperamide activation of ATP hydrolysis was biphasic implying methadone has a single binding site and loperamide has 2 binding sites on P-gp. | 29499278 |
| Type | IDs |
|---|---|
| Synonymous | Abcb4, Evi32, Mdr1a, Mdr3, P-gp, Pgp, Pgy-3, Pgy3, mdr-3 |
| Gene |
UniProtKB-ID:
MDR1A_MOUSE
UniprotKB:
P21447
UniParc:
UPI000043539C
EMBL:
M30697,
M24417,
M33580,
M33581,
CH466600,
AY864315
Ensembl:
ENSMUSG00000040584
KO:
mmu:18671
|
| Nucleutide sequences |
EMBL-CDS:
AAA39514.1,
AAW56448.1,
AAA39518.1,
AAA03243.1,
AAA39517.1,
EDL14677.1
Ensembl_TRS:
ENSMUST00000047753
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000041204
RefSeq:
NP_035206.2
|
| Others |
UniRef100:
UniRef100_P21447
UniRef90:
UniRef90_P21447
UniRef50:
UniRef50_P21447
UniGene:
Mm.207354
CCDS:
CCDS19084.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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